TWiM describes how microbiological analysis of the Gowanus Canal in Brooklyn has revealed an antimicrobial resistance reservoir and bioremediation potential, and fungicide resistance in Fusarium graminearum, the fungus recently smuggled into the US.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin


Right click to download TWiM #334 (86 MB .mp3, 60 minutes)

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Music used on TWiM is by Ronald Jenkees.

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TWiM explains how a mutualistic model bacterium can become lethal in a non-symbiotic host, and engineering a kill switch into a tuberculosis vaccine for improved safety.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin


Right click to download TWiM #333 (86 MB .mp3, 60 minutes)

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to [email protected]


TWiM explains a study of the unique and extreme microbial and chemical environment on the International Space Station, and the connection between the gut microbiome and pain in fibromyalgia.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson


Right click to download TWiM #332 (86 MB .mp3, 60 minutes)

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Music used on TWiM is by Ronald Jenkees.

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TWiM explains how to recode E. coli so it uses only one stop codon, and an exploration of the mechanisms of bacterial adhesion within dental plaque.

Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin

Guest: Mark O Martin


Right click to download TWiM #331 (86 MB .mp3, 60 minutes)

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Links for this episode

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to [email protected]


TWiM explains how to recode E. coli so it uses only one stop codon, and an exploration of the mechanisms of bacterial adhesion within dental plaque.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson


Right click to download TWiM #330 (86 MB .mp3, 60 minutes)

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to [email protected]


TWiM explains Pasteur’s relentless hunt for microbes in the air, and how bacteria hunt for prey by ixotrophy – using grappling hooks!

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Guest: Mark O. Martin


Right click to download TWiM #329 (86 MB .mp3, 60 minutes)

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to [email protected]


TWiM describes Shigella infection facilitated by interaction of human enteric α-defensin 5 with a colonic epithelial receptor, and an amino acid change in RNA polymerase that leads to resistance to β-lactams by preventing dysregulation of amino acid and nucleotide metabolism.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin


Right click to download TWiM #328 (86 MB .mp3, 60 minutes)

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to [email protected]


TWiM explains the remarkable abilities of bacterial ice nucleating proteins to promote freezing of water, and cryoprotective proteins produced by worm microbiomes that prevent freezing.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin


Right click to download TWiM #327 (86 MB .mp3, 60 minutes)

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Links for this episode

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to [email protected]


TWiM explores the discovery of microbial enzymes, PETases, that can degrade ubiquitous plastics, and how exogenous peptidoglycan is a danger signal to trigger biofilm formation.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin

Guest: Mark O. Martin


Right click to download TWiM #326 (86 MB .mp3, 60 minutes)

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Links for this episode

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Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to [email protected]


TWiM reveals that record high atmospheric methane growth has been driven by microbes, and the cecum as an adaptive niche for Salmonella typhi.

Hosts: Michael Schmidt, Michele Swanson, and Petra Levin


Right click to download TWiM #325 (86 MB .mp3, 60 minutes)

Subscribe to TWiM (free) on Apple PodcastsStitcherRSS, or by email.

Links for this episode

Become a Patron of TWiM!

Music used on TWiM is by Ronald Jenkees.

Send your microbiology questions and comments to [email protected]