TWiM explores the activation of  natural product synthesis using CRISPR interference in Streptomyces, and how light/dark and temperature cycling modulate electron flow in Pseudomonas aeruginosa biofilms.

Hosts: Vincent Racaniello, Michele Swanson, and Petra Levin

Right click to download TWiM #272 (38 MB .mp3, 52 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM presents a novel mucosal COVID-19 vaccine based on a bacteriophage capsid, and potentiation of C. difficile infection severity by the gut bacterial community.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM #271 (38 MB .mp3, 52 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM explores the use of Archaea to produce plastics from molasses wastewater, and a bacterial defense against bacteriophage infection that involves depletion of deoxynucleotides.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM #270 (38 MB .mp3, 52 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM reviews discovery of a bacterium that is visible to the naked eye, and reversible resistance to bacteriophage by shedding of the bacterial cell wall.

Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin

Right click to download TWiM #269 (35 MB .mp3, 47 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM discusses citizen science surveillance of drug-resistant Aspergillus in garden soil, and the mechanism of action of a copper dependent antibiotic.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin

Right click to download TWiM #268 (35 MB .mp3, 47 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

From ASM Microbe 2022 in Washington, DC, Heran joins TWiM to discuss her career and her work on the agent of tuberculosis, Mycobacterium tuberculosis.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Guest: Heran Darwin

Right click to download TWiM #267 (35 MB .mp3, 47 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM explains how spindle-shaped Archaeal viruses evolved from rod-shaped ancestors to package a larger genome, and transcriptional recording by CRISPR acquisition from RNA.

Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin

Right click to download TWiM #266 (37 MB .mp3, 52 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM explains the discovery of hotspots of genetic variation containing reservoirs of anti-phage systems in E. coli phages and their parasitic satellites, and pathogen desiccation tolerance promoted by hydrophilins.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM #265 (41 MB .mp3, 57 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM reveals that the atypical antipsychotic quetiapine promotes multiple antibiotic resistance in E. coli, and treatment with Bifidobacterium lactis probiotic benefits patients with coronary artery disease.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin

Right click to download TWiM #264 (48 MB .mp3, 66 minutes)

Subscribe to TWiM (free) on Apple PodcastsGoogle PodcastsStitcherAndroidRSS, or by email.

Become a Patron of TWiM!

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM explains the use of lavender oil to disrupt Listeria biofilms, and how treatment of catheters with liquid silicone reduces associated urinary tract infections.

Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Petra Levin

Right click to download TWiM #263 (57 MB .mp3, 70 minutes)

Subscribe to TWiM (free) on Apple PodcastsGoogle PodcastsStitcherAndroidRSS, or by email.

Become a Patron of TWiM!

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv