Alex joins Nels and Vincent to discuss his work which demonstrates that somatic mutation rates scale with lifespan in mammals.

Hosts: Nels Elde and Vincent Racaniello

Guest: Alex Cagan

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Science Picks 1:12:34

AlexPaper.app
NelsFifty years since Lewontin’s apportionment of human diversity
VincentAn Exceptional Village

Listener Pick

Martha Plagues Upon the Earth by Kyle Harper

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Nels and Vincent describe how a single amino acid change can allow E. coli to replace the essential gut symbiont of the stinkbug Plautia stali.

Hosts: Nels Elde and Vincent Racaniello

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Science Picks 1:13:41

NelsInequality in science and the case for a new agenda
VincentFoundations of Virology by Fred Murphy

Listener Pick

SamSaturday Morning Breakfast – Evolutionist

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Nels and Vincent review isolation of SARS-CoV-2-like viruses from bats in Laos that can replicate in human cells.

Hosts: Nels Elde and Vincent Racaniello

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  • SARS-CoV-2 like viruses in bats in Laos (Nature) 13:37
  • Vampire vax (TWiV 809) 14:51
  • Time stamps by Jolene. Thanks!

Science Picks 1:30:30

NelsErich Jarvis on scientists and public engagement
VincentPolio type 1 in Africa

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Joe Graves joins Nels and Vincent to discuss his career in evolutionary biology and his recent book that answers questions about race and racism.

Hosts: Nels Elde and Vincent Racaniello

Guest: Joe Graves

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Science Picks 1:14:43

Nels Where is Webb?
VincentBlack Microbiologists Association
JoeBiology versus bias

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Nels and Vincent review three aspects of SARS-CoV-2: phylogenetics of Omicron, a two-step fitness selection for SARS-CoV-2 variants, and putative RNA insertions from host genomes.

Hosts: Nels Elde and Vincent Racaniello

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Science Picks 1:23:33

Nels Plant virus satellite accelerates wing formation in insect
VincentA plant virus that switched to vertebrates

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Nels and Vincent discuss evolutionary evidence for an epidemic of coronavirus infection over 20,000 years ago in East Asia, and reconstruction of the membrane differences between bacteria and Archaea reveals unexpected differences in permeability.

Hosts: Nels Elde and Vincent Racaniello

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Science Picks 1:01:50

Nels Slowed canonical progress in large fields of science
VincentVirology Live

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Nels and Vincent explain a method to calculate the mutation rate of SARS-CoV-2, and the role of a single amino acid change in spike in enhancing fitness of the delta variant and enabling it to out-compete the alpha variant.

Hosts: Nels Elde and Vincent Racaniello

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Science Picks 1:13:51

Nels Leading Edge Symposium
VincentEpidemiological and evolutionary dynamics of SARS-CoV-2

Listener Pick

ThomasThe gene’s-eye view of evolution by J. Arvid Ågren

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Carl Zimmer joins Nels to talk about science writing, science communication, viruses, and his new book, On Life’s Edge.

Host: Nels Elde

Guest: Carl Zimmer

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Science Picks 1:11:10

Nels Remembrance of Dick Lewontin
CarlFrom telomere to telomere: the transcriptional and epigenetic state of human repeat elements

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Nels and Vincent discuss the identification of novel bat coronaviruses that shed light on the evolution of SARS-CoV-2, dating the first cases of COVID-19 to mid-November 2019, and recovery of deleted genome sequences from early in the Wuhan outbreak.

Hosts: Nels Elde and Vincent Racaniello

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Science Picks 1:14:03

Nels The Last—And Only—Foreign Scientist in the Wuhan Lab Speaks Out
VincentHuman Behavior During the Pandemic Is More Important Than Any Covid Variant

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Nels and Vincent explain a new method for calculating the most recent common ancestor of SARS-CoV-2, which concludes that the ancestral virus was circulating in October/November 2019, before its first detection in China.

Hosts: Nels Elde and Vincent Racaniello

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Science Picks 1:24:20

Nels Ed Yong pandemic trauma and We’re Not Ready for the Next Pandemic
VincentFurin cleavage site is not a smoking gun

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