TWiV 158: Wolverines go viral

Hosts: Vincent Racaniello, Rich Condit, Alice Telesnitsky, and Kathy Spindler

Vincent and Rich visit the Microbiology and Immunology Department at the University of Michigan Medical School, and speak with Alice and Kathy about their work on HIV genome dimerization, and packaging and pathogenesis of mouse adenovirus.

Model of poliovirus bound to CD155 made by Stefan Taube.

Click the arrow above to play, or right-click to download TWiV 158 (52 MB .mp3, 87 minutes).

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Links for this episode:

• Mouse adenovirus infection of macrophages (Virology)
• Breakdown of blood-brain barrier by mouse adenovirus (J Virol)
• Major locus for mouse adenovirus susceptibility (J Immunol)
• Structures in HIV 5′-end that regulate genome packaging (Science)
• Packaging of host RNAs by murine leukemia virus (J Virol)
• What, how, when, where, and why of retroviral genome dimerization and packaging (PLoS Path)
• Virologist replaces Steve Jobs at Apple
• TWiV on Facebook
• Letters read on TWiV 158

Weekly Science Picks

Alice – Banvard’s Folly by Paul S. Collins
Kathy – The world at seven billion
Rich – The Princess Bride
Vincent – Center for the history of microbiology

Listener Pick of the Week

Tim – Dead Ends to Somewhere by Richard L. Ward
Don – Ben Goldacre: Battling bad science (TED)

Send your virology questions and comments to twiv@microbe.tv.