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Tag: splicing

  • Netcast

TWiV 346: A double helical career

  • July 19, 2015
  • Tagged as: bacteriophage, Francis Crick, Jim Watson, Joan Steitz, microrna, mRNA, non-coding RNA, R17, Shine-Delgarno, snRNA, snRNP, splicing, translation, viral, virology, virus

This episode was recorded at the 34th Annual Meeting of the American Society for Virology, where Vincent, Rich, and Kathy spoke with Joan Steitz, a tireless promoter of women in science and one of the greatest scientists of our generation.

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  • Netcast

TWiV 339: Herpes and the sashimi plot

  • May 31, 2015
  • Tagged as: cancer, Chikungunya virus, exon, herpesvirus, host shutoff, intron, IRF7, Lassa fever, mosquitoes, splicing, transcription termination, translation, viral, virology, virus, west nile virus

Tre TWiV amici present three snippets and a side of sashimi: how herpesvirus inhibits host cell gene expression by disrupting transcription termination.

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  • Netcast

TWiV 328: Lariat tricks in 3D

  • March 15, 2015
  • Tagged as: 3Dpol, coxsackievirus, enterovirus, enterovirus 71, mRNA, NLS, nuclear localization signal, nucleus, picornavirus, poliovirus, Prp8, RdRp, rhinovirus, RNA polymerase, snurp, spliceosome, splicing, viral, virology, virus

The TWiVocateurs discuss how the RNA polymerase of enteroviruses binds a component of the splicing machinery and inhibits mRNA processing.

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