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Tag: spliceosome

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TWiV 462: Splicing RNA with Phillip A. Sharp

  • October 8, 2017
  • Tagged as: exon, intervening sequence, intron, lariat, Phillip A. Sharp, rna splicing, spliceosome, split genes, viral, virology, virus, viruses
TWiV

Vincent speaks with 1993 Nobel Laureate Phillip A. Sharp about his career and his seminal discovery of RNA splicing in mammalian cells, which changed our understanding of gene structure.

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  • Netcast

TWiV 328: Lariat tricks in 3D

  • March 15, 2015
  • Tagged as: 3Dpol, coxsackievirus, enterovirus, enterovirus 71, mRNA, NLS, nuclear localization signal, nucleus, picornavirus, poliovirus, Prp8, RdRp, rhinovirus, RNA polymerase, snurp, spliceosome, splicing, viral, virology, virus

The TWiVocateurs discuss how the RNA polymerase of enteroviruses binds a component of the splicing machinery and inhibits mRNA processing.

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