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Tag: isg

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TWiV 534: Portal to the METTL

  • February 10, 2019
  • Tagged as: calicivirus, cryoEM, cytomegalovirus, endocytosis, HCMV, herpesvirus, IFN, isg, m6A methylation, methyl eraser, methyl reader, methyl writer, METTL, mRNA stability, portal, receptor, uncoating, viral, virology, virus, viruses

The TWiV crew reveal a unique portal on the calcivirus capsid formed upon receptor engagement, and the regulation of interferon responses in virus-infected cells by methylation of mRNA.

1 Reply
  • Netcast

TWiV 263: Game of clones

  • December 15, 2013
  • Tagged as: Ben tenOever, bracket, email, final four, influenza, interferon stimulated gene, isg, listener questions, sweet 16, viral, virology, virus, winner

Ben joins the TWiV team to reveal the winner of his contest in which influenza viruses carrying different interferon-stimulated genes vie against one another in mice.

1 Reply
  • Netcast

TWiV 180: Throwing IFIT at flu and holding a miR to HCV

  • April 22, 2012
  • Tagged as: argonaute, disease susceptibility, hcv, hepatitis, ifitm3, influenza, interferon, IRES, isg, micro rna, mIR-122, RNA, translation, viral, virology, virus

Vincent, Alan, and Rich review association of an interferon-induced protein with severe influenza, and stabilization of HCV RNA by a microRNA.

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