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Tag: histone

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TWiV 543: Stoned and senile

  • April 14, 2019
  • Tagged as: alzheimer's disease, amoebae, dementia, giant virus, herpes simplex virus 1, histone, horizontal gene transfer, Medusavirus, memory loss, mouse model, NCLDV, neurodegereration, reactivation, viral, virology, virus, viruses

The TWiV team discusses Medusavirus, isolated from a hot spring in Japan, and induction of hallmarks of neurodegeneration by recurrent herpes simplex virus 1 infection of mice.

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TWiV 530: Quiet please!

  • January 13, 2019
  • Tagged as: DNA integration, histone, histone acetylation, histone methylation, HUSH complex, NP220, retrovirus, transcriptional silencing, viral, virology, virus

Steve Goff returns to TWiV to discuss the work of his laboratory on how retroviral genomes are silenced in infected cells.

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TWiV 369: Camel runny noses and other JNK

  • December 27, 2015
  • Tagged as: camel, chromatin, coronavirus, herpes simplex virus, herpesvirus, histone, immunity, JNK, MERS, MERS-CoV, methyl/phospho switch, methylation, neuronal stress, phosphorylation, reactivation, shedding, Vaccine, viral, virology, virus, viruses
TWiV

A swarm of virologists discusses testing of a MERS coronavirus vaccine for camels, and how a neuronal stress pathway reactivates herpes simplex virus.

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