Vincent, Rich, and Brianne discuss a study estimating the fraction of symptoms and severe disease after SARS- CoV-2 infection, cellular immune responses without seroconversion during interfamilial infections, and answer listener email.

The TWiV team summarizes serology-based tests for SARS-CoV-2, lack of effect of ACE inhibitors or ARBs on COVID-19 severity, and answers listener questions.

For the first TWiV of 2020 we reveal that microbiome depletion with antibiotics alters the immune response to influenza vaccine, and how successive blood meals facilitate virus dissemination in mosquitoes and transmission potential.

Lynda Coughlan joins the weekly virtual bus companions for a discussion of a host defense peptide from frogs that destroys influenza virus, and mouse models for acute and chronic hepacivirus infection.

Four virologists discuss our current understanding of Zika virus biology, pathogenesis, transmission, and prevention, in this special live episode recorded at the American Society for Microbiology in Washington, DC.

Preprint servers, the structure of an antibody bound to Zika virus, blocking Zika virus replication in mosquitoes with Wolbachia, and killing carp in Australia with a herpesvirus are topics of this episode hosted by Vincent, Dickson, Alan, and Kathy.