In this episode of TWiM, the hidden biochemical diversity in soil-dwelling Actinobacteria that could lead to a second Golden Era of antibiotic discovery, and structures of glideosome components reveals the mechanism of gliding in apicomplexan parasites.
Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt
Right click to download TWiM #229 (39 MB .mp3, 53 minutes)
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Links for this episode
- Cryptic or silent? (mBio)
- The Streptomyces chromosome (Ann Rev Gen)
- Engineering Nature’s Medicines (pdf)
- Apicomplexan glideosome (Comm Biol)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
Dear TWiM,
As a gardener I find this topic so interesting. I do really enjoy the smell of soil, I guess that’s kind of gross.
This gliding mechanism reminds me of how snails or slugs move when watching them on glass. It’s really beautiful imagery.
Thanks for a fascinating podcast!
Jennifer Fallon