The Fellowship of the TWiM reveal that colorectal cancer-associated microbiota are associated with higher numbers of methylated genes in colonic mucosa, and identification of metabolites needed by the fire blight disease bacterium for virulence in apples.
Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt
Right click to download TWiM#211 (57 MB .mp3, 78 minutes)
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Links for this episode
- Colorectal cancer and the gut microbiome (PNAS)
- Fire blight (YouTube)
- Fire blight spreads north (NY Times)
- E. amylovora auxotrophs (Appl Environ Micro)
- Image credit
- Letters read on TWiM 211
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to [email protected]
That is crazy the one that Carol sent was the plague in China Report its crazy how this was then China’s biggest outbreak prior to COVID-19
Dear Vincent,
“Both my parents died of colon cancer.” — Your comment in the episode when you discussed taking aspirin as prevention against colon cancer.
I have never heard anyone else who had said that and it echoed in my heart and brain. Both of my parents died of colon cancer, too; my mother at the age of 52 in 1975 and my dad (Italian descent) at the age of 68 in 1992. I could never fathom how both of them died of the same disease. So, it could be bacterial as well as genetic? Of course, your comment to me will be that you hope I am getting regular colonoscopies. Yes! And I am so grateful that the polyps (adenomatous) can be removed. No complaining from me on the prep for the procedure. It’s a terrible disease. I will speak with my doctor about taking aspirin. Have the finding of this study been incorporated into clinical practice?
Regards,
Nancy
Aged 72
PS The weather is cool and blustery today — currently 34 degrees F.