TWiM 194: Standard imperial procedure

How a bacterium helps dengue virus replicate in the mosquito gut, and minicells as a damage disposal mechanism in E. coli.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter

Right click to download TWiM#194 (32 MB .mp3, 65 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 193: Persisters

The TWiM team explore how Lactobacillus reuteri can rescue social deficits in three mouse models of autism spectrum disorder, and the role of Salmonella persisters in undermining host defenses during antibiotic treatment.

Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

Right click to download TWiM#193 (29 MB .mp3, 61 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 192: A Qtip for phages

Armillaria gallica

The TWiM team reveals an extremely low rate of mutation in a 2500 year old, 185 acre fungus in Michigan, and how a host-produced quorum sensing autoinducer controls the phage switch between lysis and lysogeny.

Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson

Right click to download TWiM#192 (30 MB .mp3, 62 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 191: By the pulp of their teeth

tooth-cross-sectionThe TWiM team reveals the oldest human plague from 4,900 years ago in Sweden, and engineering E. coli to become an endosymbiont in yeast, modeling the evolution of mitochondria.

Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson

Right click to download TWiM#191 (30 MB .mp3, 62 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 190: Exosomes in your nose and in your gut

exosomesThe TWiM-opods consider two stories about exosomes, vesicles that are shed from cells: those that eliminate airway pathogens, and those from the plants we eat that shape our gut microbiome.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM#190 (35 MB .mp3, 71 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 189: Salmonella BonJovi

worlds fungiThe TWiM team considers the state of the world’s fungi as revealed by a report from the Kew Royal Botanical Gardens, and how Salmonella loses motility to evade host defenses.

Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson

Right click to download TWiM#189 (35 MB .mp3, 71 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 188: Turducken antibiotics

dna-rnaThe TWiM rock stars show how to modify gram-positive antibiotics so they can kill gram-negative cells, and bacteria that have both DNA and RNA in their genome.

Hosts: Vincent Racaniello and Michael Schmidt

Right click to download TWiM#188 (39 MB .mp3, 81 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 187: Rounding up the bees

HoneybeesThe TWiM people reveal that phages must cooperate to overcome CRISPR-Cas defenses, and the effect of the herbicide glyphosate on the gut microbiome of honey bees.

Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson

Right click to download TWiM#187 (32 MB .mp3, 66 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 186: Crypto-metamorphosis

Gigantopelta chessoiaThe TWiM team describe the involvement of a microbiome in snail metamorphosis, and using Listeria to kill tumors.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM#186 (35 MB .mp3, 73 minutes)

Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

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Links for this episode

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to [email protected]

TWiM 185: There’s no moa Moa

moaThe TWiM team considers the increasing tolerance of Enterococcus to handwash alcohols, and how the study of DNA in ancient dung reveals the diet and parasite burden of extinct New Zealand birds.

Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter and Michele Swanson

Right click to download TWiM#185 (33 MB .mp3, 68 minutes)

Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Become a Patron of TWiM!

Links for this episode

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to [email protected]

The Hosts of TWiM

Petra Levin, Ph.D.


Michele Swanson, Ph.D.


Michael G. Schmidt, Ph.D.


Vincent Racaniello, Ph.D.


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