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Tag: mutational signature

  • Episode

TWiEVO 46: Can an old tumor teach us new tricks?

  • August 31, 2019
  • Tagged as: APOBEC, cancer lineage, canine transmissible tumor, evolution, mutational signature, natural selection, somatic evolution

Nels and Vincent analyze the genomes of canine transmissible tumors to provide insight into the worldwide spread of the disease from its origin in a single dog 4000-8500 years ago, and its diversity, mutation, and evolution.

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The Hosts of TWiEVO

Nels Elde, Ph.D.


Vincent Racaniello, Ph.D.


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