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Category: Episode

  • Episode

TWiEVO 48: Flipping out with choanos on caffeine

  • October 30, 2019
  • Tagged as: actomyosin, choanoflagellate, contraction, evolution, light regulated contraction, multicellularity, natural selection, phosphodiesterase, rhodopsin

Nels and Vincent reveal a new choanoflagellate that forms multicellular cup shaped colonies that respond to light to alternate between feeding and swimming behavior.

1 Reply
  • Episode

TWiEVO 47: On the origin of beer species

  • September 19, 2019
  • Tagged as: admixture, ale, allele, beer yeast, evolution, fermentation, lager, natural selection, polyploidy, recombination, Saccharomyces cerevisiae, wine

Nels and Vincent trace the origins of Saccharomyces cerevisiae strains used to make beer, and find that ales and lagers are made with yeasts that were derived from those used to make European grape wine and Asian rice wine.

1 Reply
  • Episode

TWiEVO 46: Can an old tumor teach us new tricks?

  • August 31, 2019
  • Tagged as: APOBEC, cancer lineage, canine transmissible tumor, evolution, mutational signature, natural selection, somatic evolution

Nels and Vincent analyze the genomes of canine transmissible tumors to provide insight into the worldwide spread of the disease from its origin in a single dog 4000-8500 years ago, and its diversity, mutation, and evolution.

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  • Episode

TWiEVO 45: Microbial secrets of mouse-ear cress

  • July 29, 2019
  • Tagged as: agricultural disease, agriculture, Arabidopsis thaliana, evolution, microbiome, monoculture, OTU, plant pathogen, Pseudomonas

At ASM Microbe in San Francisco, Nels and Vincent meet up with Talia Karasov who reveals that in contrast to agriculture, wild plants are colonized by multiple lineages of pathogenic bacteria.

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  • Episode

TWiEVO 44: The enemy of my enemy is my phage

  • June 27, 2019
  • Tagged as: antimicrobial efflux pump, antimicrobial resistance, evolution, Mycobacterium, phage therapy, Pseudomonas, viral, virus, virus entry, viruses

At ASM Microbe in San Francisco, Nels and Vincent meet up with Paul Turner to talk about evolutionary considerations in using bacteriophages to treat infections with antibiotic-resistant bacteria.

4 Replies
  • Episode

TWiEVO 43: Social evolution with a side of shrimp

  • May 25, 2019
  • Tagged as: ecology, evolution, genome architecture, snapping shrimp, social behavior, social transitions, Synalpheus

Dustin Rubinstein joins Nels and Vincent to discuss coevolution of genome architecture and social behavior, and studying social transitions in sponge-dwelling snapping shrimp.

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  • Episode

TWiEVO 42: Who’s who in your genome

  • April 24, 2019
  • Tagged as: adaptation, archaic human, Denisovan, evolution, genome sequences, hominid, introgression, natural selection, Papuans

Nels and Vincent review the contribution of multiple Denisovan lineages to the modern Papuan genome.

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  • Episode

TWiEVO 41: Where do baby genes come from?

  • March 20, 2019
  • Tagged as: adaptive evolution, antifreeze protein, de novo gene, evolution, natural selection, nogenic, noncoding gene, noncoding origin, northern codfish, proto-ORF

Nels and Vincent explore the evolution of new protein-coding genes de novo from nocoding DNA sequences, using the antifreeze protein of northern codfish as a model.

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  • Episode

TWiEVO 40: Eau de bee

  • February 15, 2019
  • Tagged as: courtship display, evolution, natural selection, odorant receptor, olfactory receptor, orchid bee, reproductive isolation, speciation, species identity

Nels and Vincent move back to reproductive isolation – this time, pre-zygotic, in the charismatic orchid bee where the males make chemically distinct perfumes to attract mates of the same species.

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  • Episode

TWiEVO 39: In a Legionella of their own

  • January 26, 2019
  • Tagged as: amoeba, DOT/ICM, effector proteins, evolution, evolve, horizontal gene transfer, host range, intracellular bacteria, Legionella

Nels and Vincent look at the intracellular bacteria Legionella from an evolutionary perspective: the role of gene acquisition and reshuffling from plants, animals, fungi, and archaea in the emergence of human pathogens.

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The Hosts of TWiEVO

Nels Elde, Ph.D.


Vincent Racaniello, Ph.D.


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