Jimmy writes:

Hi guys

I am a frequent Swedish listener who have some questions about the PUUV-Virus. In 2008 I was lucky to get hemorrhagic fever with renal syndrome caused by the PUUV-Virus (large outbreak between 2007-2008, due to peak in vole cycle). Why I addressed myself as “lucky” is because I did my MsC thesis in zoonoses (Borrelia burgdorferi), and I feel great about having tried it. I have also tried borreliosis, but that was not as nearly as painful as my light hemorrhagic fever. In Sweden the PUUV-Virus only persists in the Northern regions, and about 50-2000 cases are reported yearly. The reservoir of the virus here in Sweden is bank voles (Myodes glareolus).

Anyway, my question is:

  1. Could you guys dedicate some time to explain the micro- / molecular biology and pathogenesis of these viruses and maybe the Swedish variant which humoristically are called “North Land Ebola”?
  2. Do you know any post disease symptoms (years after the infection)?

Best regards




Mark writes:

My masters student daughter was assigned to listen to TWIV.

As the great father that I am, uhem, cough, I have made her aware of TWIV, TWIM, and TWIP since I started listening, several years ago.

She sent a text to me saying, “I chose #356, Gut Viriome in children who are malnourished.”

Trying to sound half as smart as my daughter, –Wiki, and I wrote back,

“as opposed to virome which more commonly refers to a collection of nucleic acids contained by viruses in a microbiome.”

Her texted response, “Oh, typo on my part,”

That was not my point, but now I have to ask,

Did you use Viriome when you should have used Virome?

She’s thinks you have it right, but I think that was a quick way to say I don’t really care dad!, vs trying find the answer, I think you got it wrong.

What do you say?


Long time listener, you often put me to sleep,  (at night.) 🙂

Richard writes:


Anthony writes:

TWiV Weather report — an ancient tradition?


Stephen writes:

Hey Twivome,

I wanted to submit this article from the Guardian for a pick of the week:

Amitabh Bachchan: ‘Forget the Avengers, it took real heroes to make India polio-free’

The content isn’t groundbreaking for TWIV but I thought you’d appreciate the headline and it gives Vincent and Alan (and everyone else) a chance to talk about the state of polio eradication (unless you’ve done that recently–I’m not currently caught up).