The eTWiVicators review evidence that the HIV-1 group O epidemic began with a single cross-species transmission of virus from western lowland gorillas.
Vincent, Dick, and Alan review a new macaque model for HIV-1 infection, a possible role for Epstein-Barr virus in multiple sclerosis, accidental release of H5N1 by a vaccine company, resistance of frogs to virus infection, and extreme virology – the biggest and smallest viruses and viral genomes.