In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about the recent Salmonella typhimurim outbreak, the ousting of another CBER director, confirmation of a new CDC director and results of a recent pool about vaccine safety and trust before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, a new anti-influenza antibody that can be combined with neuraminidase inhibitors, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the effectiveness of Sinopharm’s COVID-19 vaccine, where to find PEMGARDA, safety of the JN.1 updated vaccine, long COVID treatment center, where to go for answers to your long COVID questions, the prevalence of cardiac and pulmonary abnormalities found via medical imaging following COVID-19 and contacting your federal government representative to stop the assault on science and biomedical research.

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Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.

TWiV explains a cohort study of over one million Danish children which shows no evidence supporting an increased risk for autoimmune, atopic or allergic, or neurodevelopmental disorders associated with early childhood exposure to vaccines with aluminum-base adjuvants, and a study of antibodies induced by mRNA-1273 and NVX-CoV2373 COVID-19 vaccines which show that polyclonal antibodies against a single site on the
spike N-terminal domain show immunodominance, high diversity, and limited crossreactivity, indicating the need to direct antibody responses away from this site.

Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker

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Weekly Picks 1:42:56

BrianneMHC Class I Antigen Presentation Video
AlanWe Become What We Behold
Vincent New Injectable Recommended by Europe for HIV Prevention

Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about how flies transmit H5N1 to humans via their feet and milk, the recent pertussis oubreak and measles epidemic before Dr. Griffin discusses monoclonal antibody therapy can enrich for RSV variants before deep diving into recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the effectiveness of Sinopharm’s COVID-19 vaccine, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, how mast cell activation can enhance long COVID and contacting your federal government representative to stop the assault on science and biomedical research.

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Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.

From the 2025 annual meeting of the American Society for Virology, Charlie Rice, 2020 Nobel Laureate in Physiology or Medicine, talks with Vincent and Kathy about his career and the scientific difficulties he and his laboratory encountered in their attempts to achieve replication of hepatitis C virus in cells in culture.

Hosts: Vincent Racaniello and Kathy Spindler

Guest: Charlie Rice

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Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello have a morning chat about the measles epidemic and H5N1 in cows before Dr. Griffin discusses how vaccination associates with reduced dementia risk before deep diving into recent statistics on measles epidemic, RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, a potential new influenza antiviral drug, whether or not the NB.1.8.1 variant should be included in the fall 2025 vaccines, immunization recommendations for COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, associaton of remesdivir administration and long-term sequelae and contacting your federal government representative to stop the assault on science and biomedical research.

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  • Wastewater for measles (WasterWater Scan)
  • Measles cases and outbreaks (CDC Rubeola) 2:28
  • Weekly measles and rubella monitoring (Government of Canada) 6:11
  • Measles (WHO)
  • Get the FACTS about measles (NY State Department of Health)
  • Measles (CDC Measles (Rubeola))
  • Measles vaccine (CDC Measles (Rubeola))
  • Presumptive evidence of measles immunity (CDC)
  • Contraindications and precautions to measles vaccination (CDC)
  • Measles (CDC Measles (Rubeola))
  • Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
  • Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
  • Deaths following vaccination: what does the evidence show (Vaccine)
  • Measles vaccine recommendations from NYP (jpg)
  • The impact of highly pathogenic avian influenza H5N1 virus infection on dairy cows (Nature) 9:17
  • Avian flu exacts heavy financial toll on dairy industry, report says (CIDRAP) 9:17
  • Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines (Journal of Experimental Medicine)
  • Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
  • US respiratory virus activity (CDC Respiratory Illnesses)
  • Respiratory virus activity levels (CDC Respiratory Illnesses)
  • Weekly surveillance report: clift notes (CDC FluView)
  • FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
  • RSV: Waste water scan for 11 pathogens (WastewaterSCan)
  • US respiratory virus activity (CDC Respiratory Illnesses)
  • ENFLONSIA: novel drug approvals 2025 (FDA)
  • RSV-Network (CDC Respiratory Syncytial virus Infection)
  • Systematic review and expert consensus on the use of long-acting monoclonal antibodies for prevention of respiratory syncytial virus disease: ARMADA (Advancing RSV Management And Disease Awareness) Taskforce (OFID) 15:18
  • Waste water scan for 11 pathogens (WastewaterSCan) 17:40
  • COVID-19 deaths (CDC)
  • COVID cases likely rising in half of states, CDC estimates (CBS News)
  • Estimated COVID-19 Periodicity and Correlation with SARS-CoV-2 Spike Protein S1 Antigenic Diversity, United States (Emerging Infectious Diseases)
  • Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
  • COVID-19 national and regional trends (CDC) 17:20
  • COVID-19 variant tracker (CDC)
  • Estimated COVID-19 Periodicity and Correlation with SARS-CoV-2 Spike Protein S1 Antigenic Diversity, United States (Emerging Infectious Diseases) 19:32
  • SARS-CoV-2 genomes galore (Nextstrain)
  • Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bi0rXiv)
  • This CDC Resignation Should Scare You (Substack: Beyond the Noise)
  • ACIP: COVID-19–Associated Hospitalizations — COVID-NET, April 2025 Update (CDC: National Center for Immunization and Respiratory Diseases))
  • Where to get pemgarda (Pemgarda)
  • EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
  • Infusion center (Prime Fusions)
  • CDC Quarantine guidelines (CDC)
  • NIH COVID-19 treatment guidelines (NIH)
  • Drug treatments for mild or moderate covid-19: systematic review and network meta-analysis (BMJ) 23:25
  • Drug interaction checker (University of Liverpool)
  • Paxlovid (Pfizer)
  • Infectious Disease Society guidelines for treatment and management (ID Society)
  • Extended nirmatrelvir–ritonavir treatment durations for immunocompromised patients with COVID-19 (EPIC-IC) (LANCET: Infectious Diseases) 26:25
  • Molnupiravir safety and efficacy (JMV)
  • Convalescent plasma recommendation for immunocompromised (ID Society)
  • What to do when sick with a respiratory virus (CDC)
  • Managing healthcare staffing shortages (CDC)
  • Steroids, dexamethasone at the right time (OFID)
  • Anticoagulation guidelines (hematology.org)
  • Daniel Griffin’s evidence based medical practices for long COVID (OFID)
  • Long COVID hotline (Columbia : Columbia University Irving Medical Center)
  • The answers: Long COVID
  • Invivyd and Leading Researchers Form SPEAR (Spike Protein Elimination and Recovery) Study Group to Assess the Effects of Monoclonal Antibody Therapy for Long COVID and COVID-19 Post-Vaccination Syndrome (INVIVYD) 31:39
  • Reaching out to US house representative
  • Letters read on TWiV 1236 35:35
  • Dr. Griffin’s COVID treatment summary (pdf)
  • Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

Content in this podcast should not be construed as medical advice.

David Barton, Brian Kempf, and Olve Peersen join TWiV to discuss RNA recombination among enteroviruses and its role in foiling poliovirus eradication.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Guests: David Barton, Brian Kempf, and Olve Peersen

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Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello note that history is being rewritten for justification of changes in COVID vaccine guidelines including myocarditis incidence and the Great Barrington Declaration ignoring presentations at the April 2025 ACIP, the response by the medical community to these changed guidelines, before Dr. Griffin discusses how vaccination associates with reduced dementia risk before deep diving into recent statistics on measles epidemic, RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, a potential new influenza antiviral durg, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, immunization recommendations for COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, associaton of remesdivir administration and long-term sequelae and contacting your federal government representative to stop the assault on science and biomedical research.

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Download TWiV 1234 (35 MB .mp3, 57 min)
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Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.

TWiV covers FDA Director overriding scientists on COVID shots, NIH funded science must now be free to read instantly, Trump cuts subscriptions to Springer Nature journals, UK and Gates make up for US money withdrawn from GAVI, US defunding USAID could lead to 14 million deaths by 2030, then reviews research on how host IL1 genetics regulates Epstein-Barr virus reactivation and long COVID, and enhanced antiviral capacity of bat innate immunity.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

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Weekly Picks 1:38:13

RichUnraveling Mendel’s final mysteries: A genomic retelling of pea genetics (Thanks, Kathy!) (Original article)
AlanWinners of Nature’s 2025 “Scientist at Work” photo competition
Vincent Signs of AI-generated text found in 14% of biomedical abstracts last year

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are shocked at how vaccine safety is undercut by misrepresenting thimerosal safety, its removal from vaccines, and how CBER director Vinay Prasad overruled his advisors for the administration of COVID vaccines to pregnant people knowingly compromising their health, before Dr. Griffin reviews recent statistics on measles epidemic, RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, immunization recommendations for COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, association of long COVID and cognitive changes as well as the development of type I diabetes and contacting your federal government representative to stop the assault on science and biomedical research.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

Content in this podcast should not be construed as medical advice.

TWiV discusses Sen. Cassidy calling for ACIP meeting delay, RFK Jr. abandons GAVI, millions of children at risk as global vaccination rates fall, RFK Jr. grilled by Congress, autism rates have increased 60-fold due to changed definitions, deep mutational scanning of rabies virus glyoprotein, and and proton gradient and incomplete TCA cycle in a giant virus.

Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Angela Mingarelli

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Weekly Picks 1:39:00

Angela 27 new, exciting, and blobby species discovered in the Peruvian rainforest!
BrianneEncounters in the Milky Way
RichWhere to go for accurate, up-to-date vaccine information 1:45:36
VincentThe members of RFK Jr.’s new vaccine committee have published little on vaccines

Listener Picks

CharlesVaccine Advice, Vandalized
KenGolden Goose Awards

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.