TWiM explains how a mutualistic model bacterium can become lethal in a non-symbiotic host, and engineering a kill switch into a tuberculosis vaccine for improved safety.
Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin
Right click to download TWiM #333 (86 MB .mp3, 60 minutes)
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Links for this episode
- When a mutualist becomes lethal (mBio)
- A lasting symbiosis (Nat Rev Micro)
- A kill switch for BCG (Nat Micro)
- Engineering mycobacteria for vaccination (Nat Micro)
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Music used on TWiM is by Ronald Jenkees.
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