The TWiM rock stars show how to modify gram-positive antibiotics so they can kill gram-negative cells, and bacteria that have both DNA and RNA in their genome.
Hosts: Vincent Racaniello and Michael Schmidt
Right click to download TWiM#188 (39 MB .mp3, 81 minutes)
Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.
Become a Patron of TWiM!
Links for this episode
- Bacterial genome with DNA and RNA (J Am Chem Soc)
- Antibiotics for gram-positives that kill gram-negatives (J Med Chem)
- Sideromycin commentary (Am Council Sci Health)
- Letters read on TWiM 188
- Transcript of this episode (html or pdf)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
Guys,
Many thanks for another really interesting episode – I am studying antibiotics so I may use the turducken paper – and am also interested in phage therapy. I knew it was big in Georgia (Eliavia centre) and in Poland but I hadn’t realised other groups were so advanced. Also on the subject of your listener’s letters on the environment -.it is important to remember we are all in this together.. It reminds me of Thomas Paine’s comment “the world is my country and my religion is to do good”. Even though he ended up on the wrong side in the eighteenth century…..