TWiM reveals quorum-sensing systems that regulate intestinal inflammation and permeability caused by P. aeruginosa, and how plasmids manipulate bacterial behavior through translational regulatory crosstalk.
The TWiM folk explore disruption of a Burkholderia intracellular niche by a cell death program, and an increase in Brucella infectiousness after intracellular passage.
Foodie TWiM reveals that bacteria in human saliva are major components of Ecuadorian indigenous beers, and an unusual E. coli that produces atypical light cream-colored colonies in chromogenic agar.
In this episode, how DNA of giant viruses has contributed extensively to the genome of green algae, and inhibition of E. coli virulence by a metabolic product of arachidonic acid in the intestinal epithelium.
Dickson joins the TWiM team to discuss the nasal microbiota of dairy farmers, and attenuation of bacterial virulence by quorum sensing in the maize weevil.
At Microbe 2017 in New Orleans, the TWiM team speaks with Arturo Casadevall about his thoughts on the pathogenic potential of a microbe, rigorous science, funding by lottery, and moonshot science.
The TWiMers get together at ASM Microbe 2016 in Boston to speak with David and Vanessa to talk about their work on regulation of bacterial virulence in the gut by bacterial adrenergic sensors, and the physiological mechanisms that make us ill and that help us recover.
From the ASM Biodefense and Emerging Diseases Research meeting, Vincent speaks with Rebekah and Wyndham about their work on Rift Valley Fever virus and other vector-borne pathogens, and the evolution and pathogenesis of Yersinia pestis, the agent of plague.
Vincent, Elio, Michael, and Michele review how microbial virulence can be increased as a consequence of community surveillance and adaptation to macrophages.
On episode #28 of the podcast, Vincent, Michael, and Elio review how competition within a host drives virulence of Streptococcus pneumoniae, and the expanding universe of the bacterial cytoskeleton.
About the Hosts of TWiM
Vincent Racaniello, Ph.D. (@profvrr) is Higgins Professor of Microbiology & Immunology at Columbia University Medical Center. He has been studying viruses for over 40 years. He teaches virology to undergraduate and graduate students, as well as medical, dental, and nursing students. His lectures are available online at iTunes University, YouTube, and Coursera.
Michael Schmidt, Ph.D. (TWiM) is the Professor and Vice Chairman of Microbiology and Immunology and Director of the Office of Special Programs at the Medical College of South Carolina. Dr. Schmidt is leading a team of infectious disease specialists from three health sciences centers and engineers from industry.