TWiM reveals high rates of co-transformation of plasmids in E. coli overturns the clonality myth, and bacterial membrane vesicles as a novel strategy for extrusion of the antimicrobial bismuth in H. pylori.

The arrival in the US of plasmid-mediated resistance to colistin antibiotics, a last line of defense against many gram-negative bacilli, and a quorum sensing system in a eukaryote are topics of this episode hosted by Vincent, Michael, and Michele.