Mark O Martin is TWiM-adjacent for this discussion of a Fusobacterium nucleatum clade that dominates colorectal cancer, and surface colonization by Flavobacterium johnsoniae promotes its survival in a model microbial community.
TWiM reviews a case of E. faecium bacteremia treated with combination bacteriophage and antibiotic therapy, and how dopamine receptor D2 confers colonization resistance via microbial metabolites.
TWiM discusses the identification of natural products from reconstructed ancient bacterial genomes, and how plant mRNAs move into a fungal pathogen via extracellular vesicles to reduce infection.
TWiM reviews the ongoing cholera outbreak in Africa, and research showing that gut complement induced by the microbiota blocks pathogens and spares commensal bacteria.
TWiM reveals a new population in the blue cheese-making fungus Penicillium roqueforti and identification of a quorum-sensing autoinducer and siderophore in uropathogenic Escherichia coli.
TWiM provides thoughts on providing better training for a non-academic career, and help celebrate Black in Microbiology Week with a 2023 paper by Ari Kozik, a co-founder of Black Microbiologists Association and Assistant Professor at the University of Michigan.
TWiM discusses a dispute about whether the mycobiome plays a role in the development of cancer, and the structure and function of channels that are delivered to plant cells by pathogenic bacteria.
TWiM reveals that breast milk bioactives are essential for development of the infant microbiome and immunity, and how capsule mutants of Klebsiella pneumoniae can affect bacterial pathogenesis.
TWiM explores the relationship between the gut microbiome and depressive symptoms, and how purine nucleotides act as adjuvants to antibiotics.
TWiM reveals that the atypical antipsychotic quetiapine promotes multiple antibiotic resistance in E. coli, and treatment with Bifidobacterium lactis probiotic benefits patients with coronary artery disease.
About the Hosts of TWiM
Vincent Racaniello, Ph.D. (@profvrr) is Higgins Professor of Microbiology & Immunology at Columbia University Medical Center. He has been studying viruses for over 40 years. He teaches virology to undergraduate and graduate students, as well as medical, dental, and nursing students. His lectures are available online at iTunes University, YouTube, and Coursera.
Michael Schmidt, Ph.D. (TWiM) is the Professor and Vice Chairman of Microbiology and Immunology and Director of the Office of Special Programs at the Medical College of South Carolina. Dr. Schmidt is leading a team of infectious disease specialists from three health sciences centers and engineers from industry.