TWiM explains a study that examines pathogen presence in ancient humans and concludes that zoonoses emerged 6500 years ago with the domestication of livestock, and determination of universal rules that govern plasmid copy number. Hosts:…
TWiM explores the use of gas sensors and machine learning to identify microbes and antimicrobial resistance in clinical specimens, and how a harmful algal bloom species releases thiamin antivitamins to suppress competitors. Hosts: Vincent Racaniello,…
TWiM explains two strategies for bacterial competition for resources: by laying down a slippery lipid and pushing away competitors, or by breaking open cells with a spike, liberating essential nutrients. Hosts: Vincent Racaniello, Michael Schmidt,…
TWiM describes how microbiological analysis of the Gowanus Canal in Brooklyn has revealed an antimicrobial resistance reservoir and bioremediation potential, and fungicide resistance in Fusarium graminearum, the fungus recently smuggled into the US. Hosts: Vincent…
TWiM explains how a mutualistic model bacterium can become lethal in a non-symbiotic host, and engineering a kill switch into a tuberculosis vaccine for improved safety. Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra…
TWiM explains a study of the unique and extreme microbial and chemical environment on the International Space Station, and the connection between the gut microbiome and pain in fibromyalgia. Hosts: Vincent Racaniello, Michael Schmidt, and…
TWiM explains how to recode E. coli so it uses only one stop codon, and an exploration of the mechanisms of bacterial adhesion within dental plaque. Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin Guest:…
TWiM explains how to recode E. coli so it uses only one stop codon, and an exploration of the mechanisms of bacterial adhesion within dental plaque. Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson Right…
TWiM explains Pasteur’s relentless hunt for microbes in the air, and how bacteria hunt for prey by ixotrophy – using grappling hooks! Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson Guest: Mark O. Martin Right…
TWiM describes Shigella infection facilitated by interaction of human enteric α-defensin 5 with a colonic epithelial receptor, and an amino acid change in RNA polymerase that leads to resistance to β-lactams by preventing dysregulation of…
The Hosts of TWiM
Petra Levin, Ph.D.
Michele Swanson, Ph.D.
Michael G. Schmidt, Ph.D.
Vincent Racaniello, Ph.D.