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Tag: CRISPR/cas

TWiM 272: Metabolism’s got rhythm

  • September 19, 2022

TWiM explores the activation of natural product synthesis using CRISPR interference in Streptomyces, and how light/dark and temperature cycling modulate electron flow in Pseudomonas aeruginosa biofilms

TWiM 266: Bacteria that can record

  • June 8, 2022

TWiM explains how spindle-shaped Archaeal viruses evolved from rod-shaped ancestors to package a larger genome, and transcriptional recording by CRISPR acquisition from RNA.

TWiM 148: Neanderthal dentistry

  • March 25, 2017

Vincent, Elio, and Michael reveal what Neanderthals ate from analysis of DNA in their teeth, and new CRISPR-Cas systems found in the genomes of uncultured microbes.

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The Hosts of TWiM

Petra Levin, Ph.D.


Michele Swanson, Ph.D.


Michael G. Schmidt, Ph.D.


Vincent Racaniello, Ph.D.


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