In his weekly clinical update, Dr. Griffin deep dives into the whooping cough epidemic and bird flu in big cats, and in conjunction with your host Vincent Racaniello discusses the recent case of paralytic poliomyelitis in Israel, measles outbreaks and HHS campaign for vaccine safety campaign before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, if the COVID mRNA vaccine is effective against symptomatic SARS-CoV-2 infection and hospitalization in children, where to find PEMGARDA, information for Columbia University Irving Medical Center’s long COVID treatment center, how long COVID effects one’s activities, personality and neuropsychiatric symptoms.
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Links for this episode
- Highest level of whooping cough cases in a decade (NBC News)
- Provisional pertussis surveillance report (CDC)
- Polio moves into Israel (Jerusalem Post)
- Polio today (GPEI)
- Measles- the let’s get real vaccination campaign (CDC)
- Measles fact sheet (CDC)
- Measles- near you (CDC)
- Let’s get real about childhood vaccines (HHS)
- The FACTS about childhood vaccines (HHS)
- Tigers and cougars dying from bird flu, oh my! (NY Times)
- US respiratory virus activity (CDC Respiratory Illnesses)
- Waste water scan for 11 pathogens (WastewaterSCan)
- US respiratory virus activity (CDC Respiratory Illnesses)
- Weekly surveillance report: cliff notes (CDC FluView)
- Burden of all-cause mortality following Influenza-associated hospitalizations (CID)
- Waste water scan for 11 pathogens (WastewaterSCan)
- RSV-Network (CDC Respiratory Syncytial virus Infection)
- COVID-19 deaths (CDC)
- COVID-19 national and regional trends (CDC)
- COVID-19 variant tracker (CDC)
- SARS-CoV-2 genomes galore (Nextstrain)
- Initial effectiveness of mRNA-1273 against SARS-CoV-2 infection and hospitalization in young children (OFID)
- Where to get pemgarda (Pemgarda)
- EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
- Fusion center near you….if in NY (Prime Fusions)
- CDC Quarantine guidelines (CDC)
- NIH COVID-19 treatment guidelines (NIH)
- Infectious Disease Society guidelines for treatment and management (ID Society)
- Drug interaction checker (University of Liverpool)
- Molnupiravir safety and efficacy (JMV)
- Convalescent plasma recommendation for immunocompromised (ID Society)
- What to do when sick with a respiratory virus (CDC)
- When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
- Managing healthcare staffing shortages (CDC)
- Steroids, dexamethasone at the right time (OFID)
- Anticoagulation guidelines (hematology.org)
- Daniel Griffin’s evidence based medical practices for long COVID (OFID)
- Long COVID hotline (Columbia : Columbia University Irving Medical Center)
- Long COVID and significant long COVID–associated activity limitation among adults
- (CDC: MMWR)
- 2024 Update of the RECOVER-Adult Long COVID Research Index (JAMA Network)
- About 8% of US adults have ever had long COVID, survey finds(CIDRAP)
- Real-world effectiveness and causal mediation study of BNT162b2 on long COVID risks in children and adolescents (eClinicalMedicine)
- Personality and neuropsychiatric symptoms in individuals diagnosed with long COVID(BMC Infectious Diseases)Post-COVID Condition Risk Factors and Symptom Clusters and Associations with Return to Pre-COVID Health (CID)
- Letters read on TWiV 1178 38:11
- Dr. Griffin’s COVID treatment summary (pdf)
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv
The post TWiV 1178: Clinical update with Dr. Daniel Griffin first appeared on This Week in Virology.
Re the choice between TCID50 and plaque assay. I do not have huge experience in these techniques, but I have tried to get undergraduates to do both these types of test in lab classes (for baculovirus – the students have no opportunity to infect themselves). TCID50 works well, but plaque assays have generally failed, so I guess that TCID50 is technically easier to set up, and to me appears to be less sensitive to operator error.
Loved the DENV life cycle link posted by Rich Condit. It would have been even more awesome if the could have described the formation of RC’s and their significance in the life cycle.
I just want to comment on this shakespearian phrase that Dickson said, i mean that’s not something original from shakespeare as are many things that are attributed to him, onde venes is latin or from any romance language, it’s from “¿de donde vienes? ” in spanish at least.