The Masters of the ScienTWIVic Universe discuss a novel poxvirus isolate from an immunosuppressed patient, H1N1 and the gain-of-function debate, and attenuation of dengue virus by recoding the genome.

Vincent and Kathy visit Laura Newcomb at California State University San Bernardino, where they talk about Laura’s viral tattoos, and a protein that protects the mosquito brain from lethal flavivirus infection.