potyvirus and geminivirusAnne Simon joins the TWiV team to talk about plant viruses, including plum pox virus that devastates nut and stone fruit trees, and a geminivirus protein that regulates viral DNA synthesis.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich ConditBrianne Barker, and Anne Simon

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Weekly Science Picks 1:28:33

Brianne –  Why are so many genes unstudied? (Zimmer and Yong)
AlanUnveiling the RNA World
RichSpaghetti mystery solved (PNAS paper)
DicksonScience Fair
Vincent – A PhD Lab Coat Ceremony

Listener Picks

StephenFlu vaccine myth rant by Crislip
Jolene – Research Matters in PLoS Path and PLoS Biology
NicholasCharity Matters app

Intro music is by Ronald Jenkees.

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Ned LandauNed Landau joins the TWiV team to discuss restriction of HIV replication by SAMHD1, and a viral antagonist that can be used to produce a dendritic cell vaccine.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

Guest: Ned Landau

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Weekly Science Picks 1:31:20

BrianneOnline Immunology Course
AlanBacteria Builder
Rich – 2018 Ig Nobel Prizes
DicksonBetween Fear and Hope
Ned – HUSH silencing of transposons
Vincent – Paywall publishing ban (Schlitz statement); Curry on DORA

Listener Pick

StevePaywall: Business of Scholarship and Biohazard
IslamPeer review Twitter post

Intro music is by Ronald Jenkees.

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Vincent and Dickson travel to the 44th Retrovirus meeting at Cold Spring Harbor Laboratories, where they speak with John Coffin, Stephen Hughes, Ya-Chi Ho, and Matt Takata about the meeting and their work on HIV-1.

Hosts: Vincent Racaniello and Dickson Despommier

Guests: John Coffin, Stephen Hughes, Ya-Chi Ho, and Matt Takata

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Intro music is by Ronald Jenkees.

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planarianThe TWiV team considers whether those who can do, can’t teach, and newly discovered viruses of planarians and Aplysia with the largest RNA genomes.

Hosts: Vincent Racaniello, Dickson Despommier, Alan DoveKathy Spindler and Brianne Barker

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Weekly Science Picks 1:29:11

Brianne – Climate change visualization
Alan – Anova sous vide cooker
DicksonFire season in western US
KathySunscreen in UV and The Projector Illusion
Vincent – The Usefulness of Useless Knowledge

Listener Pick

RiverThe Conscience of the Present

Intro music is by Ronald Jenkees.

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Soviet Bioweapons FacilitiesJens returns to present a brief history of bioweapons, with a focus on the program in the Soviet Union, the largest ever undertaken, and his experience working in the decommissioned Soviet bioweapons laboratory known as Vector.

Hosts: Vincent Racaniello, Dickson DespommierRich Condit, and Kathy Spindler

Guest: Jens Kuhn

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Weekly Science Picks 1:49:12

Jens – Nudibranchs, Beastly Garden, large nidovirus (one, two)
Rich –Living inside a canister
Dickson –
Global rivers and streams
Kathy – TWiM 181 Dr. Warhol’s Periodic Table of Microbes
Vincent – Twitter Bots and Russian Trolls Amplify Vaccine Debate

Intro music is by Ronald Jenkees.

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vaccinia virus proteinsThe TWiV team discuss the biology of Ebola viruses, and how localization of the membrane proteins of vaccinia virus drive function: the fusion machinery sits at the tips of virions, and binding proteins are at the sides.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

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Weekly Science Picks 1:38:52

Alan – Puzzled Escape Games
Rich – An Extremely Detailed Map of the 2016 Election
Dickson – Parker Solar Probe
Kathy – Ancient earth globe and connected Dinosaur database
Brianne
 – STEMM education should get HACD
Vincent – Free tuition for all NYU medical students

Listener Pick

HeatherGoFarm blog

Intro music is by Ronald Jenkees.

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David TullerDavid Tuller returns to provide an update of his investigative work to expose the methodological and ethical problems with the PACE trial for ME/CFS.

Host: Vincent Racaniello

Guest: David Tuller

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Intro music is by Ronald Jenkees.

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CROVThe TWiVniks explain how the three-dimensional structure of the giant Cafeteria roenbergensis virus suggests a new mode of assembly, and the apparent elimination of dengue fever in an Australian city by release of mosquitoes harboring Wolbachia.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, and Brianne Barker

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Weekly Science Picks 1:27:45

Alan – Ebola research begins at the NEIDL
Dickson – Science Photo Library

Brianne
 – First liquid water (underground lake) found on Mars
Vincent – Thirty years ago, we could have saved the planet

Listener Pick

EdmundSTEM talk

Intro music is by Ronald Jenkees.

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persistence of herpesvirusThe TWiV hosts review persistence of Ebola virus after the end of the Liberian outbreak, and the potential role of two herpesviruses in the pathogenesis of Alzheimer’s disease.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, Kathy Spindler and Brianne Barker

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Weekly Science Picks 1:44:33

Alan – Impossible Burger
Rich – SpaceX Just Sent Algae to the ISS, Here’s How It’ll Power Deep Space Missions
Dickson –
Art and Science Intersection (Art Science Museum)
Brianne
 – Why it is not a ‘failure’ to leave academia
Kathy – 2003 video history of nuclear explosions 1945 – 1998
Vincent – Revisionist History Episode 8 and Episode 9

Listener Pick

Mark – TWIV bingo (png)

Intro music is by Ronald Jenkees.

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Nipah at Outbreak ExhibitThe TWiVerinos discuss Nipah virus and the recent outbreak in India, and the first cast of polio in Papua New Guinea in 18 years.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Brianne Barker

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Weekly Science Picks 1:32:05

Alan – Glaciers of the Rockies aerial photos
Rich – SpaceX CRS-15 mission to the space station (wiki)
Dickson –
Test of Einstein’s theory of relativity
Brianne
 – biorender
Vincent – True or False? with Michael Schmidt

Listener Pick

JoleneDogs cannot get autism

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv