The TWiM rock stars show how to modify gram-positive antibiotics so they can kill gram-negative cells, and bacteria that have both DNA and RNA in their genome.
Right click to download TWiM#188 (39 MB .mp3, 81 minutes)
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Links for this episode
- Bacterial genome with DNA and RNA (J Am Chem Soc)
- Antibiotics for gram-positives that kill gram-negatives (J Med Chem)
- Sideromycin commentary (Am Council Sci Health)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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