ElioThe Masters of the Microbiological Universe discuss the humongouest fungus, and a commensal bacterium that protects against skin neoplasia.

Hosts: Vincent Racaniello, Elio SchaechterMichael Schmidt, and Michele Swanson

Right click to download TWiM#173 (35 MB .mp3, 74 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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Approvals of antibacterials

Number of antibacterial new drug application (NDA) approvals vs year intervals. Drugs limited to systemic agents.

The TWiMmers discuss culture-independent discovery of malacidin antibiotics, and unfolding of relaxase during bacterial conjugation.

Hosts: Vincent Racaniello, Elio SchaechterMichael Schmidt, and Michele Swanson

Right click to download TWiM#172 (35 MB .mp3, 74 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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Stingless bee

The stingless bee Scaptotrigona depilis

The TWiM team explores a stingless bee that requires a fungal steroid to pupate, and colonic biofilms containing tumorigenic bacteria in patients with colorectal polyps.

Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt

Right click to download TWiM#171 (29 MB .mp3, 61 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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influenza protein nanoparticleThe TWiM team reveals that spread of plague was likely by human ectoparasites, not rats, and deconstruct a durable, broadly protective protein nanoparticle influenza virus vaccine.

Host: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson

Right click to download TWiM#170 (27 MB .mp3, 56 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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Robinson Ridge

Robinson Ridge, Antarctica, looking towards Sparkes Bay.

The cast of TWiM reveals how uropathogenic E. coli use a binding protein to treat copper as a nutrient or a toxin, and Antarctic soil bacteria that survive on trace atmospheric gases.

Host: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson

Right click to download TWiM#169 (37 MB .mp3, 77 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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Maize weevilDickson joins the TWiM team to discuss the nasal microbiota of dairy farmers, and attenuation of bacterial virulence by quorum sensing in the maize weevil.

Host: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Guest: Dickson Despommier

Right click to download TWiM#168 (37 MB .mp3, 77 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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3D printing bacteriaVincent, Michael, and Michele reveal how pandemic influenza viruses suppress immunogenic cell death, and 3D printing of bacteria into functional materials.

Host: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM#167 (26 MB .mp3, 53 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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Fuel cellVincent and Elio discuss the reason for poor efficacy of one of the influenza virus vaccines, and using a hyperthermophilic anaerobe to produce hydrogen from fruit and vegetable wastes in seawater.

Host: Vincent Racaniello and Elio Schaechter

Right click to download TWiM#166 (25 MB .mp3, 51 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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The HulkThe TWiM team discusses the use of copper on exercise weights to reduce bacterial burden, and the mechanism of antigenic variation by which a fungus that causes severe pneumonia escapes the immune system.

Host: Vincent RacanielloElio Schaechter, Michael Schmidt, and Michele Swanson

Right click to download TWiM#165 (31 MB .mp3, 63 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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From Indiana University, Vincent speaks with Ankur, Julia, and Xindan about their careers and their work on horizontal gene transfer, quorum sensing, and chromosome organization in bacteria.

Host: Vincent Racaniello

Guests: Ankur Dalia, Julia Van Kessel, and Xindan Wang

Right click to download TWiM#164 (29 MB .mp3, 59 minutes)

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Links for this episode

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv