This Week in Evolution

TWiEVO 44: The enemy of my enemy is my phage

June 27, 2019

At ASM Microbe in San Francisco, Nels and Vincent meet up with Paul Turner to talk about evolutionary considerations in using bacteriophages to treat infections with antibiotic-resistant bacteria.

Hosts: Nels Elde and Vincent Racaniello

Guest: Paul Turner

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Turner Lab at Yale 1:17
Phage therapy: A renewed approach (Cell Host Microbe) 20:57
Phage treatment of aortic graft (Evol Med Pub Health) 33:22, 37:06
Time stamps by Jolene. Thanks!

Science Picks 57:19

Nels – Science Glass

Vincent – Phage therapy for disseminated Mycobacterial infection

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Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 43: Social evolution with a side of shrimp

May 25, 2019

Dustin Rubinstein joins Nels and Vincent to discuss coevolution of genome architecture and social behavior, and studying social transitions in sponge-dwelling snapping shrimp.

Hosts: Nels Elde and Vincent Racaniello

Guest: Dustin Rubinstein

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Co-evolution of genome architecture and social behavior (Trend Ecol Evol) 22:05, 31:12
Social transitions in snapping shrimp (Curr Op Insect Sci) 49:13, 41:01
Time stamps by Jolene. Thanks!

Science Picks 1:07:19

Dustin – Genesis: The Deep Origin of Societies 1 by E.O. Wilson, and The Human Swarm by Mark O. Moffett

Nels – For Love of Insects by Thomas Eisner

Vincent – Quacks blamed for Pakistan HIV-1 outbreak

Music on TWiEVO is performed by Trampled by Turtles

Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 42: Who’s who in your genome

April 24, 2019

Nels and Vincent review the contribution of multiple Denisovan lineages to the modern Papuan genome.

Hosts: Nels Elde and Vincent Racaniello

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Denisovan ancestries in Papuans (Cell) 3:12, 18:21
Prof Murray Cox 4:09
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Letters read on TWiEVO 42 1:06:48
Time stamps by Jolene. Thanks!

Science Picks 1:12:32

Nels – Sydney Brenner – What Genomes Can Tell Us About the Past

Vincent – Scientific Communication in a Post-Truth Society

Music on TWiEVO is performed by Trampled by Turtles

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TWiEVO 41: Where do baby genes come from?

March 20, 2019

Nels and Vincent explore the evolution of new protein-coding genes de novo from noncoding DNA sequences, using the antifreeze protein of northern codfish as a model.

Hosts: Nels Elde and Vincent Racaniello

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Evolution of antifreeze protein gene in codfish (PNAS) 4:13
Codfish diversity (Cheng lab) 10:03
Frankentomatoes (Huff Post) 56:41
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Time stamps by Jolene. Thanks!

Science Picks 1:15:38

Nels – Science at Sundance reviews

Vincent – The Rise and Fall of Scientific Authority

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TWiEVO 40: Eau de bee

February 15, 2019

Nels and Vincent move back to reproductive isolation – this time, pre-zygotic, in the charismatic orchid bee where the males make chemically distinct perfumes to attract mates of the same species.

Hosts: Nels Elde and Vincent Racaniello

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Olfactory receptor gene underlies reproductive isolation (biorXiv) 4:49
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Time stamps by Jolene. Thanks!

Science Picks 59:59

Nels – Nature Zen: Orchid Bees Are Shiny
Vincent – What You Believe About Science Denial May Be All Wrong

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Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 39: In a Legionella of their own

January 26, 2019

Nels and Vincent look at the intracellular bacteria Legionella from an evolutionary perspective: the role of gene acquisition and reshuffling from plants, animals, fungi, and archaea in the emergence of human pathogens.

Hosts: Nels Elde and Vincent Racaniello

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Over 18,000 effectors in Legionella genome (PNAS) 4:08
Carmen Buchrieser lab 4:31
Howard Shuman 10:04
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Science Picks 1:06:46

Nels – Science in Film (twitter)
Vincent – Lunar Eclipse 101

Music on TWiEVO is performed by Trampled by Turtles

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TWiEVO 38: Evolving to evolve

December 24, 2018

Nels and Vincent reveal a highly conserved protein that acts as an evolvability factor, increasing mutation and the ability of bacteria to become resistant to antibiotics.

Hosts: Nels Elde and Vincent Racaniello

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Inhibiting evolution of antibiotic resistance (Mol Cell) 1:47
Pushing viruses over the error threshold (virology blog) 48:22
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Letters read on TWiEVO 38 57:58

Science Picks 1:11:48

Nels – Science/nature illustrator/artist Rachel Ignotofsky (website, Etsy shop)
Vincent – Life Ascending by Nick Lane

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Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 37: A tangled tree on the Quammens

November 17, 2018

David Quammen joins Nels and Vincent to talk about his new book, A Tangled Tree, including evolutionary trees, Carl Woese, Lynn Margulis, horizontal gene transfer, and much more.

Hosts: Nels Elde and Vincent Racaniello

Guest: David Quammen

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David’s website 00:52
David on TWiV 408, Boston Quammens 2:08
Axel Erlandson’s trees reimagined – Gilroy Gardens 1:22:39

Music on TWiEVO is performed by Trampled by Turtles

Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 36: All’s not quiet on the telomeric front

October 24, 2018

Mia joins Nels and Vincent to unravel their finding that the transposons that maintain the ends of chromosomes in Drosophila have evolved in conflict with the genome.

Hosts: Nels Elde and Vincent Racaniello

Guest: Mia Levine

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Levine Lab at U Penn 1:34
Telomere elongation without telomerase (bioRxiv) 9:57
Letters read on TWiEVO 36 57:05

Science Picks 1:06:43

Nels – Cinema Science podcast
Vincent – Mastodon bones unearthed (Instagram, Grand Rapids News)

Music on TWiEVO is performed by Trampled by Turtles

Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 35: Strawberry sex chromosomes forever

September 21, 2018

Nels and Vincent reveal that female-specific DNA associated with sex in strawberries has repeatedly changed its genomic location, possibly linking new genes with sex.

Hosts: Nels Elde and Vincent Racaniello

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Jumping sex genes in strawberries (PLoS Biol) 5:17, 36:29
Red Queen by Matt Ridley 17:11
Image credit
Letters read on TWiEVO 35 1:02:03

Science Picks 1:19:52

Nels – New snailfish and Cloned crayfish
Vincent – A PhD Lab Coat Ceremony

Listener Picks

Steve – Diversity in simple blobs
Justin – On Growth and Form by D’Arcy Wentworth Thompson (free)

Music on TWiEVO is performed by Trampled by Turtles

Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 44: The enemy of my enemy is my phage

Science Picks 57:19

TWiEVO 42: Who’s who in your genome

Science Picks 1:12:32

TWiEVO 41: Where do baby genes come from?

Science Picks 1:15:38

TWiEVO 40: Eau de bee

Science Picks 59:59

TWiEVO 39: In a Legionella of their own

Science Picks 1:06:46

TWiEVO 38: Evolving to evolve

Science Picks 1:11:48

TWiEVO 37: A tangled tree on the Quammens

TWiEVO 36: All’s not quiet on the telomeric front

Science Picks 1:06:43

TWiEVO 35: Strawberry sex chromosomes forever

Science Picks 1:19:52

Listener Picks

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