nextstrain.org

Nels and Vincent continue their discussion of SARS-CoV-2 from an evolutionary viewpoint, focusing on what the genome sequences tell us about the virus.

Hosts: Nels Elde and Vincent Racaniello

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Download TWiEVO 53 (56 MB .mp3, 92 min)
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Science Picks

Nels – Science Mill Explorer Zone
VincentCOVID-19 treatment and therapy tracker

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Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent examine SARS-CoV-2 from an evolutionary viewpoint, examining what the spike glycoprotein sequence informs us about the origin of the virus.

Hosts: Nels Elde and Vincent Racaniello

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Download TWiEVO 52 (50 MB .mp3, 93 min)
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Science Picks 1:18:59


Nels – Alejandro Sanchez TED Talk
VincentWHO SARS-CoV-2 Sitrep

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helix-loop-helix

Nels and Vincent dive deep into evolution and consider how new proteins emerged billions of years ago, when there were no other proteins to serve as starting material.

Hosts: Nels Elde and Vincent Racaniello

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Download TWiEVO 51 (43 MB .mp3, 71 min)
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Science Picks 1:01:10


Nels – Universal principled review
VincentHostile Planet by National Geographic

Listener Pick

Courtney – Nightwish Endless Forms Most Beautiful and Shudder Before The Beautiful

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Nels and Vincent discuss signatures of sex chromosome evolution revealed by assembly of a young vertebrate Y chromosome from 3-spined stickleback fish.

Hosts: Nels Elde and Vincent Racaniello

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Download TWiEVO 50 (62 MB .mp3, 103 min)
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Science Picks


Nels – Genome from a 5,700-Year-Old Wad of Chewed Gum
VincentNJ Sea-Level Rise Reports

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Rich joins Nels and Vincent for a debriefing on the 4th Ringberg Symposium on Giant Virus Biology in Tegernsee, Germany.

Hosts: Nels Elde and Vincent Racaniello

Guest: Rich Condit

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Download TWiEVO 49 (68 MB .mp3, 113 min)
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Science Picks 1:42:56

Rich – Flightradar24
Nels – Deutsches Museum Munich
VincentDiversify Microbiology

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Nels and Vincent reveal a new choanoflagellate that forms multicellular cup shaped colonies that respond to light to alternate between feeding and swimming behavior.

Hosts: Nels Elde and Vincent Racaniello

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Download TWiEVO 48 (57 MB .mp3, 94 min)
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Science Picks 1:24:00

Nels – How to write a great science paper by Cormac McCarthy
VincentNatural Selection Store

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Nels and Vincent trace the origins of Saccharomyces cerevisiae strains used to make beer, and find that ales and lagers are made with yeasts that were derived from those used to make European grape wine and Asian rice wine.

Hosts: Nels Elde and Vincent Racaniello

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Download TWiEVO 47 (56 MB .mp3, 92 min)
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Science Picks 1:21:24

Nels – Population fluctuations in 10 biggest cities
Vincent1.7 million year old rhino tooth (original Nature paper)

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Nels and Vincent analyze the genomes of canine transmissible tumors to provide insight into the worldwide spread of the disease from its origin in a single dog 4000-8500 years ago, and its diversity, mutation, and evolution.

Hosts: Nels Elde and Vincent Racaniello

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Download TWiEVO 46 (56 MB .mp3, 92 min)
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Science Picks 1:21:48

Nels – Vasa Museum in Stockholm
VincentNobel Museum in Stockholm

Listener Pick

Irene@EndlessForms and #PlantScienceFascinatesMe #plantsday

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At ASM Microbe in San Francisco, Nels and Vincent meet up with Talia Karasov who reveals that in contrast to agriculture, wild plants are colonized by multiple lineages of pathogenic bacteria.

Hosts: Nels Elde and Vincent Racaniello

Guest: Talia Karasov

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Download TWiEVO 45 (38 MB .mp3, 62 min)
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Music on TWiEVO is performed by Trampled by Turtles

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Talia Karasov

At ASM Microbe in San Francisco, Nels and Vincent meet up with Paul Turner to talk about evolutionary considerations in using bacteriophages to treat infections with antibiotic-resistant bacteria.

Hosts: Nels Elde and Vincent Racaniello

Guest: Paul Turner

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Download TWiEVO 44 (39 MB .mp3, 65 min)
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Science Picks 57:19

Nels – Science Glass

VincentPhage therapy for disseminated Mycobacterial infection

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