Something a bit different this episiode. Last month, we joined Jesse Noar, host of the excellent Bacteriophiles podcast to record an episode about oncolytic viruses (viruses that blow up cancer cells). We hope you enjoy it, then head on over to microbeworld and subscribe to Jesse’s podcast.

In this episode, how parasitic worms alter in immunomodulatory effects of the gut microbiome. Also, Kate expresses her distaste for large datasets and animal experiments, and Matt proposes a weight loss company that will only market to identical twins.

In this episode, we talk about the innate immune system’s Trojan cow strategy – using a cyclic dinucleotide as a signaling molecule means that viruses can package the seeds of their own destruction. Meanwhile, Matt and Kate throw Kevin under the bus with regards to alcohol consumption, and Matt expounds on the security threat posed by infectious cattle.

This week, we’re discussing DRACOs – not the Harry Potter character, a “new” class of antiviral therapeutics that links up the double-stranded RNA-binding part of one protein to the cell-death (apoPtosis)-activating part of a different protein.