TWiEVO 41: Where do baby genes come from?
- Nels and Vincent explore the evolution of new protein-coding genes de novo from nocoding DNA sequences, using the antifreeze protein of northern codfish as a model. post
BacterioFiles 378: Medusa makes marble microbes
- This episode: Newly discovered giant virus from a hot spring turns its amoeba hosts to stone! post
TWiV 539: Multitudes contain me
- The TWiV hosts present two potentially seminal papers, on long-distance chemoattraction of a host by a chlorovirus, and replication of a nanovirus across multiple cells in a plant. post
BacterioFiles 377: Distributed Defense-Defeating Devices
- This episode: Newly discovered CRISPR-inhibiting genes are found in many different bacterial groups! post
TWiV 538: An Iowa caucus of viruses
- TWiV travels to the University of Iowa to speak with Wendy Maury and Stanley Perlman about their research on Ebolavirus entry and coronavirus pathogenesis. post
BacterioFiles 376: Pressurized pollutant pulls products
- This episode: Supercritical carbon dioxide and bacteria that can grow in it make a great combination for biofuel production! post
TWiM 195: Gingipain in the Alzheimer brain
- Michael and Vincent discuss the finding of immunity to Cas9 protein in humans, and a potential role for an oral bacterium in Alzheimer’s disease. post
TWiV 537: Boundary issues
- The Scholars of the Podcast reveal ribosomal proteins encoded in viral genomes, and a protein cell receptor for bat influenza viruses. post
TWiP 167: The constipated mathematician
- The Tremendous Trio solve the case of the Woman With Steatorrhea, and reveal breakdown of the glycocalyx associated with severe and fatal malaria. post
BacterioFiles 375: Prepared Pathogen Preserves Perception
- This episode: A cancer-killing virus could help increase success of treatment of a form of eye cancer in children! post
TWiV 536: A flock of seagulls, a herd of seals
- Vincent and Alan travel to Tufts Veterinary School where they meet up with members of the Runstadler lab to talk about their work on influenza virus circulation in water birds and seals. post
Curiosity 8: It's in their genes (nucleic acids I)
- What is DNA and how is it so fundamentally important to how each of us develop? Today, we’ll discuss DNA, the central dogma, and twins. post
TWiP 166: From remote locations
- The Podfessors solve the case of the Teenager With Swollen Scrotum, and continue the story arc of Daniel's favorite cells, B-1 cells, and their association with protective immune responses in human Chagas disease. post
TWiEVO 40: Eau de bee
- Nels and Vincent move back to reproductive isolation - this time, pre-zygotic, in the charismatic orchid bee where the males make chemically distinct perfumes to attract mates of the same species. post
TWiM 194: Standard imperial procedure
- How a bacterium helps dengue virus replicate in the mosquito gut, and minicells as a damage disposal mechanism in E. coli. post
Curiosity 7: Grab Bag I
- Today we’ll discuss individuals who think they’re more capable than they are; how one determines what reputable information is; coffee without a filter; and, how to be scientifically conversational. post
Immune 17: Feed a macrophage, starve a tumor
- The immunophiles explain how metabolic rewiring of macrophages by CpG promotes clearance of cancer cells. post
Curiosity 6: Batteries: Zap, but How?
- Much of humankind has become increasingly more dependent on portable electrical energy. What is a battery? post
TWiM 193: Persisters
- The TWiM team explore how Lactobacillus reuteri can rescue social deficits in three mouse models of autism spectrum disorder, and the role of Salmonella persisters in undermining host defenses during antibiotic treatment. post
Curiosity 5: How old are ferns?
- Ferns are boring and they look like old houseplants! Well, slow your roll there. Some of these plants' relatives were around before the mega-continent Pangea broke apart. post
TWiP 165: The sound of crackles
- The TWiP team solve the case of the Four Year Old with Fever, Headache, and Cough, and discuss the release of extracellular vesicles from Leishmania amazonensis that manipulate the host immune response. post
TWiEVO 39: In a Legionella of their own
- Nels and Vincent look at the intracellular bacteria Legionella from an evolutionary perspective: the role of gene acquisition and reshuffling from plants, animals, fungi, and archaea in the emergence of human pathogens. post
Immune 16: B is for Bursa
- The Immune team turns to chickens, which have been important in understanding the immune system, to show that infection of mature B cells is not required for the pathogenesis of Marek's disease herpesvirus. post
TWiM 192: A Qtip for phages
- The TWiM team reveals an extremely low rate of mutation in a 2500 year old, 185 acre fungus in Michigan, and how a host-produced quorum sensing autoinducer controls the phage switch between lysis and lysogeny. post
TWiP 164: Surf n' perf
- The TWiP legends solve the case of Surfer Sans Septum, and discuss how two symbiotic bacteria in the tsetse fly might allow colonization with Trypanosoma brucei. post
TWiEVO 38: Evolving to evolve
- Nels and Vincent reveal a highly conserved protein that acts as an evolvability factor, increasing mutation and the ability of bacteria to become resistant to antibiotics. post
Immune 15: Happy neu-trophil year
- Stephanie takes the Immune team on a tour of neutrophils, the most abundant leukocytes in mammals, including tethers and slings, neutrophil rolling, and neutrophil nets. post
Immune 14: Braking bad
- The Immune team explains the science behind the 2018 Nobel Prizes awarded to Allison and Honjo: checkpoint immunotherapy. post
Urban Agriculture 29: Gotham Greens
- Dickson travels to indoor farm Gotham Greens in Brooklyn, New York to speak with Co-founder and CEO Viraj Puri. post
Buckyball viruses
- How to build several types of virus particles using the small, powerful magnets called Buckyballs. post
Urban Agriculture 28: The Vertical Farm Institute
- Daniel joins Dickson and Vincent to talk about the Vertical Farm Institute, which provides advice and planning on the design and construction of indoor farms. post
Urban Agriculture 27: The Next Big Things
- Dickson provides an updates on progress towards establishing long-term, sustainable, local, safe food systems based on indoor farming. post
omega tau 239: The Saturn V Launch Vehicle
- David Woods has a new book out, so of course he has to talk about it on omega tau 🙂 His recent book is about the Saturn V launch vehicle, i.e., this time it is about the rocket, not about the spaceship. In this episode we dive into lots of details that we did not cover in the two Apollo episodes (episodes 83 and 97) — make sure you have listened to those before you listen to this one. post
omega tau 238: Societal Complexity, Part II: Today’s Perspective
- In October 2015, Joseph Tainter was my guest in omega tau 184 to discuss his concept of increasing complexity and eventual collapse of societies. In this episode, our guest Paul Arbair discusses these concepts in the light of today’s rising populism in several countries. The episode is based on two articles Paul wrote on his blog: one on Brexit and one on Trump. post
omega tau 237: Synthesizers
- Late 2016, during a trip to the Netherlands, I visted Rutger Vlek of River Creative Technology in his home studio to record an episode about synthesizers. We talked about the basics of sound generation, various enveloping and filtering techniques, sound design, the different fundamental approaches of sound synthesis, as well as a couple of classic synths. Rutger illustrated lots of approaches with samples from some of his many synthesizers. post
omega tau 236: Space flight software
- Last fall I visited ESTEC, ESA’s space research and technology center. In this first of three episodes, I talk with Maria Hernek, who heads the Flight Software Systems section. We talk about the challenges of space flight software, the development processes used by ESA and its vendors, as well as means of ensuring the required quality attributes. This episode can be seen as a continuation of the conversation with Andreas Wortmann in the OHB episode. post
Public Health United 45: Rush Holt on Science & Politics
- From his earliest days, Dr. Rush Holt has been interested in “how the world works (that’s science) and how people get along (that’s politics).” post
Public Health United 44: Ellis Rubinstein, New York Academy of Sciences President
- Ellis Rubinstein, President of the New York Academy of Sciences, discusses how important it is for young scientists to be involved in AAAS and NYAS, and to not limit membership and activism to just those in their later careers as some other scientific societies do. post
Public Health United 43: Modernizing Science Education With Emily Fisher and Arvin Saleh
- Nina teams up with her Communicating Science student Arvin Saleh and his advisor Dr. Emily Fisher to talk about the wave that’s been hitting undergraduate campuses with the aim of improving how we teach science. post
Public Health United 42: Meghan Moran On Persuasive Communication
- Our latest guest, Dr. Meghan Moran, researches how the tobacco industry uses persuasive messaging on youths and teens–and how public health policy makers can use that knowledge to implement prevention campaigns post
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