TWiEVO 51: De novo emergence of proteins
- Nels and Vincent dive deep into evolution and consider how new proteins emerged billions of years ago, when there were no other proteins to serve as starting material. post
TWiV 583: Galveston virus hunters
- Vincent and Rich travel to Galveston National Laboratory to speak with Jim LeDuc, Tom Ksiazek, and Bob Tesch about their long careers as virus hunters. post
TWiV 582: This little virus went to market
- TWiV provides updates on the new coronavirus causing respiratory disease in China, the current influenza season, and the epidemic of African swine fever, including determination of the three-dimensional structure of the virus particle. post
TWiP 179: Verminous visitors
- The TWiP DVD solve the case of the Child Who Passed Worms, and discuss a non-human primate model for severe malarial anemia. post
Immune 27: Trained immunity
- Steph explains how sepsis induces protective immune memory in NK cells, via histone methylation of the interferon gamma enhancer. post
TWiM 211: Bacteria, colon cancer, and fire blight
- The Fellowship of the TWiM reveal that colorectal cancer-associated microbiota are associated with higher numbers of methylated genes in colonic mucosa, and identification of metabolites needed by the fire blight disease bacterium for virulence in apples. post
TWiN 4: It's a trap!
- Jason visits the TWiN studio to explain Arc Capsid Bearing Any RNAs (ACBARs), virus-like capsids that transfer genetic information between neurons. post
TWiV 581: Alimentary particles
- For the first TWiV of 2020 we reveal that microbiome depletion with antibiotics alters the immune response to influenza vaccine, and how successive blood meals facilitate virus dissemination in mosquitoes and transmission potential. post
TWiV 580: Noncoding RNA with Chris Sullivan
- From the University of Texas at Austin, Vincent and Rich speak with Chris Sullivan about his work on miRNAs encoded in the genomes of polyomaviruses and papillomaviruses, and how an RNA triphosphatase restricts hepatitis C virus replication. post
TWiEVO 50: I'm dreaming of a Y chromosome
- Nels and Vincent discuss signatures of sex chromosome evolution revealed by assembly of a young vertebrate Y chromosome from 3-spined stickleback fish. post
TWiN 3: Gambling on dopamine
- Erin and the TWiN team explain how dopamine neurons encode reward probability and uncertainty, and their roles in attention-based learning and risk-taking such as gambling and addiction. post
TWiM 210: The Waze of microbes
- The Microbial Comrades present the oldest osteosynthesis in history, and how a small molecule produced by stressed bacteria is a warning signal that repels healthy populations to promote their survival. post
TWiP 178: The shadowlands of medicine
- The Knights of the TWiP solve the case of the Man Who Lost Weight, and discuss a Plasmodium protein kinase that is a malarial drug target. post
TWiEVO 49: A giant podcast on giant viruses
- Rich joins Nels and Vincent for a debriefing on the 4th Ringberg Symposium on Giant Virus Biology in Tegernsee, Germany. post
Immune 26: Measles erases immune memory
- Michael Mina joins the Immune team to explain his findings that measles diminishes pre-existing antibodies that protect against infection with other pathogens. post
TWiM 209: Resuscitating persisters and flagellotrophic phage
- The TWiM team reveals how ribosome modification resuscitates bacterial persister cells, and explain how a phage tail fiber protein exploits rotation of flagella to move towards the cell membrane. post
TWiP 177: A scabrous education
- The TWiPsters solve the case of the Rashy Schoolteacher, and reveal a drug from rotifers that live on the snail intermediate host which paralyzes schistosome cercariae and prevents infection of mice. post
TWiN 2: Cells that fire together wire together
- The TWiN team explain the basic principles of synaptic transmission, and review a classic paper demonstrating that recycling endosomes are important for modifying synaptic strength, which is involved in information storage and processing. post
Immune 25: Remembrance of antigen encounters past
- The Immune team explains that short chain fatty acids produced by microbial fermentation of fiber rewire metabolism to enable the production of memory T cells. post
TWiM 208: Georgia Tech microbial
- At Georgia Tech, members and trainees of the Center for Microbial Dynamics and Infection discuss the identification of pathogen essential genes during coinfections, and how coral management can improve coral defenses against pathogens. post
TWiEVO 48: Flipping out with choanos on caffeine
- Nels and Vincent reveal a new choanoflagellate that forms multicellular cup shaped colonies that respond to light to alternate between feeding and swimming behavior. post
TWiN 1: The ultimate challenge
- The synaptics launch the first episode of TWiN by revealing their training, research interests, and goals for the podcast. post
TWiP 176: Blood schmear
- The TWiPpers of the bite fantastic solve the case of the Indian Man Who Hiked, and discuss the effects of schistosome soluble egg antigen on infection of lymphocytes with HIV-1. post
Immune 24: Unlucky IL-13
- The Immune team reveals a new type of T helper cell that drives the production of IgE, leading to allergic responses. post
Urban Agriculture 29: Gotham Greens
- Dickson travels to indoor farm Gotham Greens in Brooklyn, New York to speak with Co-founder and CEO Viraj Puri. post
Buckyball viruses
- How to build several types of virus particles using the small, powerful magnets called Buckyballs. post
Urban Agriculture 28: The Vertical Farm Institute
- Daniel joins Dickson and Vincent to talk about the Vertical Farm Institute, which provides advice and planning on the design and construction of indoor farms. post
Urban Agriculture 27: The Next Big Things
- Dickson provides an updates on progress towards establishing long-term, sustainable, local, safe food systems based on indoor farming. post
Zika in the guys
- In this episode of Virus Watch, we explore the finding that Zika virus infects the testis of mice, causing damage to the organ, reduced sperm production, and less fertility. The important question: does the same happen in humans? post
Urban Agriculture 26: Green Sense Farms
- Dickson and Vincent speak with Robert Colangelo, founding farmer and CEO of Green Sense Farms, the world's largest commercial indoor vertical farm. post
Cancer Killing Viruses
- Guest host Lynda Coughlan reviews how oncolytic viruses, which specifically kill tumor cells, are designed and how they work. post
Polio in Nigeria
- Polio returns to Nigeria after two years - but it turns out it had never gone away. post