Vincent, Alan, and Marc discuss using a virus for beetle control, RNA based gene therapy for AIDS, and reconstitution of a endogenous human retrovirus.
Vincent and Rich travel to the Blood Systems Research Institute in San Francisco to speak with Eric Delwart about his work on virus discovery.
Vincent, Alan, Rich, and special guest Dr. Kirsten Sanford talk about her career in science media, then consider whether smallpox eradication led to the AIDS pandemic, high fidelity RNA synthesis, and a new Ebola virus vaccine.
Vincent and Rich answer listener questions on viruses and gluten allergy, RNA silencing, influenza virus, herpes simplex virus, HIV/AIDS, chronic fatigue syndrome, manicure salons, and the koala tea of Marseilles.
Vincent, Alan, and Marc talk about chronic wasting disease of deer caused by prions, blocking the semen-derived enhancer of HIV infection with surfen, and making green transgenic rabbits using a lentiviral vector.
Vincent and Dickson continue virology 101 with a discussion of information flow from RNA to DNA, a process known as reverse transcription, which occurs in cells infected with retroviruses, hepatitis B virus, cauliflower mosaic virus, foamy viruses, and even in uninfected cells.
Vincent, Alan, and Rich discuss ten compelling virology stories of 2009.
Vincent, Dickson, and Alan discuss STEP HIV-1 vaccine failure caused by the adenovirus vector, presence of West Nile virus in kidneys for years after initial infection, adaptation of the influenza viral RNA polymerase for replication in human cells, and the significance of the D225G change in the influenza HA protein.
Vincent visited Scotch Plains – Fanwood High School and talked about viruses with high school biology students.
Vincent and Dr. Scott Hammer talk about different types of AIDS vaccines and how they are tested in clinical trials.