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Tag: enhancer

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TWiV 382: Everyone’s a little bit viral

  • March 27, 2016
  • Tagged as: AIM, CHiP, computational biology, crispr, endogenous retroviruses, enhancer, erv, IFN, inflammasome, interferon, retrovirus, STAT1, transposable element, viral, virology, virus, viruses
TWiV

Nels and Ed join the TWiV team to talk about their observation that regulation of the human interferon response depends on regulatory sequences that were co-opted millions of years ago from endogenous retroviruses.

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  • Netcast

TWiV 279: The missing LNC

  • April 6, 2014
  • Tagged as: differentiation, embryonic stem cells, endogenous retrovirus, enhancer, erv, ES cells, HERV-H, pluripotency, transcription, viral, virology, virus

Vincent, Alan, and Kathy reveal how a retrovirus in the human genome keeps embryonic stem cells in a pluripotent state, from where they can differentiate into all cells of the body.

1 Reply
  • Netcast

TWiV 272: Give peas a chance

  • February 16, 2014
  • Tagged as: aphid, capsid, enation, enhancer, erv, genetically modified organism, GMO, human endogenous retrovirus, pea, plant, schizophrenia linked gene PRODH, spider toxin, viral, virology, virus

The TWiV team describes aphid control by using a viral capsid protein to deliver a spider toxin to plants, and a human endogenous retrovirus that enhances expression of a neuronal gene.

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