Netcast TWiV 222: Jumpin’ Jack Flash, it’s a GAS GAS GAS March 3, 2013 Tagged as: cGAMP, cGAMP synthase, cyclic GAMP, DNA sensor, innate immune response, second messenger, viral, virology, virus The complete TWiV team discusses the amazing finding that cyclic GMP-AMP synthase is a cytosolic innate immune DNA sensor.