Ari and Kishana, two of the founders of Black in Microbiology, join TWiV to discuss the goals of the organization, then we review pauses of J&J and Lilly COVID-19 vaccine trials, preclinical studies of Regeneron’s SARS-CoV-2 monoclonal antibody cocktail, reinfection of a patient in Nevada, and listener questions.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler and Brianne Barker

Guest: Ari Kozik and Kishana Taylor

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Weekly Science Picks 1:52:22

BrianneA Lab of One’s Own by Rita Colwell
Kathy –  Endonym map
Rich“The Coronavirus Unveiled” by Carl Zimmer
VincentPrinciples of Virology 5th Edition

Listener Pick

LesCoronavirus cake
MaryChoir finds a way to sing

Intro music is by Ronald Jenkees

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Daniel Griffin provides a clinical report on COVID-19, then Amy joins us to discuss the 2020 Chemistry Nobel Prize for gene editing using CRISPR/Cas9, continuing circulation of poliovirus in Afghanistan, inborn errors of interferon in patients with severe COVID-19, and listener questions.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Guests: Daniel Griffin and Amy Rosenfeld

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Download TWiV 671 (102 MB .mp3, 170 min)
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Weekly Science Picks 2:38:37

AmyCoronavirus : A book for children by Kate Wilson and Nia Roberts
AlanLost Prologue
RichRAPS COVID-19 vaccine tracker
VincentA Crack in Creation by Doudna and Sternberg and Sternberg on TWiM 184

Intro music is by Ronald Jenkees

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Kizzmekia Corbett joins TWiV to review her career and her work on respiratory syncytial virus, influenza virus, and coronaviruses and coronavirus vaccines, including her role in development and testing of a spike-encoding mRNA vaccine, and then we review the Nobel Prize for discovery of hepatitis C virus.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler and Brianne Barker

Guest: Kizzmekia Corbett

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Weekly Science Picks 1:58:26

BrianneCOVID-19 in Molecular Detail for Teaching
Kathy – Mars shining brightest since 2003
RichLost Prologue
VincentGirl from Ipanema is weirder than you thought

Listener Pick

SandraLearn Medical Research

Intro music is by Ronald Jenkees

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Daniel Griffin discusses President Trump’s case of COVID-19, including the clinical course, the medications he received and why, and expectations for the next few weeks.

Host: Vincent Racaniello

Guest: Daniel Griffin

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Download TWiV Special (20 MB .mp3, 34 min)
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Intro music is by Ronald Jenkees

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Daniel Griffin provides a clinical report on COVID-19, including a discussion of the role of vitamin D in COVID-19, Michael and Christopher explain why we have made all the wrong moves during the pandemic, evidence that the D614G amino acid change improves transmission in hamsters, and listener questions.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker

Guests: Daniel Griffin, Michael B. Yaffe, and Christopher D. Barrett

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Download TWiV 669 (108 MB .mp3, 180 min)
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Weekly Science Picks 2:46:13

DicksonWhy we should all wear masks
BrianneMilestones in Vaccines
RichWallpaper/fabric designs by David Goodsell
VincentDas Coronavirus bullet points and a new t-shirt

Listener Pick

JustinCOVID Alert NY App | Department of Health

Intro music is by Ronald Jenkees

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Tony Schountz joins TWiV to explain the work of his laboratory showing that deer mice can be infected with and transmit SARS-CoV-2, and how his colony of Jamaican fruit bats is being used to understand their response to virus infections.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler and Brianne Barker

Guest: Tony Schountz

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Weekly Science Picks 1:36:20

BrianneVirus Masks
Kathy – UV in the vineyards (video)
RichGreat White Shark Attack
VincentSmart WiFi garage door opener

Intro music is by Ronald Jenkees

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Daniel Griffin provides a clinical report on COVID-19, review of the phase I and II trials of the Russian prime-boost vaccine, a mouse model that recapitulates age-dependent severe disease, and listener questions.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Guest: Daniel Griffin

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Weekly Science Picks 2:28:50

DicksonRewilding Europe
AlanHow to Do Nothing by Jenny Odell
RichGene drive engineered mosquitoes
VincentTWiEVO 60 with 12 guests!

Intro music is by Ronald Jenkees

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David Brenner joins TWiV to explain how far-UVC lights could provide protection from SARS-CoV-2 and other airborne viruses in public places, solutions to face mask fogging, transmission during airplane flights, and listener questions.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler and Brianne Barker

Guest: David Brenner

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Weekly Science Picks

Kathy – Comedy wildlife photo awards and ISS transits Mars

Intro music is by Ronald Jenkees

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Daniel Griffin provides a clinical report on COVID-19, superspreading potential of SARS-CoV-2 in Hong Kong, structure of virion glycoprotein of a commmon cold coronavirus reveals changes driven by prolonged circulation in humans, and listener email.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

Guest: Daniel Griffin

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Download TWiV 665 (106 MB .mp3, 177 min)
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Intro music is by Ronald Jenkees

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On this mid-week edition, does it matter that SARS-CoV-2 is mutating, seasonal coronavirus immunity is short-lived, another bogus claim that the virus was produced in a laboratory (it came from Nature), and answers to listener questions.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler and Brianne Barker

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Download TWiV 664 (73 MB .mp3, 122 min)
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  • Coronavirus is mutating (Nature) 9:29
  • Seasonal CoV immunity is short (Nat Med) 18:16
  • Sorry, no link to the fake science document! 40:44
  • Letters read on TWiV 664 1:08:02
  • Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv