Johnye writes: Wouldn’t have known about AAV but for you and Dr. King. Thank you. Johnye http://hms.harvard.edu/news/ancestry-design?utm_source=Silverpop&utm_medium=email&utm_content=s1&utm_campaign=08.17.15.HMS Johnye Ballenger, M. D., FAAP Johnye writes: Does this qualify as “gain of function”? “According to Vandenberghe, generating…
Vincent, Alan and Rich explain how to make a functional ribosome with tethered subunits, and review the results of a phase III VSV-vectored Ebolavirus vaccine trial in Guinea.
Robin writes: Overcrowding and virulence Genes are no longer genes if they do not survive. Those that do not adapt disappear. An adaptation to high transmissibility with episodic transmission in pathogenic microbes might allow high…
Vincent and Rich discuss fruit fly viruses, one year without polio in Nigeria, and a permissive Marek’s disease viral vaccine that allows transmission of virulent viruses.
Steve writes: Hi Vincent, I listened to your latest TWiM, the other day (I’ve caught up with them all now!), and thought you sounded not your usual bright and breezy self: Voice was lower and…
Robin writes (TWiV 332): Thanks for the wide perspective The co-option of host machinery to serve essential functions and the concomitant shrinking of genomes can follow two paths thereafter. If the invader earns its keep,…
The TWiV team discusses the possible association of the respiratory pathogen enterovirus D68 with neurological disease.
The TWiV team reviews identification of immune biomarkers in CFS/ME patients, and how a cell nuclease controls the innate immune response to vaccinia virus infection.
The TWiVocateurs discuss how the RNA polymerase of enteroviruses binds a component of the splicing machinery and inhibits mRNA processing.
Suzanne writes: Your conversation reminded me that I’ve heard people say they can smell some cancers. Usually lung cancer and usually on someone’s breath. My husband was diagnosed with colon cancer several years ago and…
The Hosts of TWiV
Vincent Racaniello, Ph.D.
Dickson D.
Despommier, Ph.D.
Alan Dove, Ph.D.
Daniel Griffin, M.D.,
Ph.D., CTropMed CTH
Jolene Ramsey, Ph.D.