TWiM describes successful phage therapy against a mycobacterial lung infection, and how encapsulation of the cell wall protects S. pneumoniae from its major peptidoglycan hydrolase and host defenses.
The TWiM team pays a tribute to Chris Condayan, and investigates the synergy between virus and the innate immune system for clearing bacterial pneumonia by phage therapy.
A eukaryote without a mitochondrion, and using a phage enzyme to eliminate intracellular bacteria are two topics discussed by the TWiMers on this episode.