TWiM 129: Dried and wrinkled, smooth and mucoid

TestHosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

The arrival in the US of plasmid-mediated resistance to colistin antibiotics, a last line of defense against many gram-negative bacilli, and a quorum sensing system in a eukaryote are topics of this episode hosted by Vincent, Michael, and Michele.

Right click to download TWiM#129 (51 MB .mp3, 71 minutes)

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Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world’s best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv.

TWiM 128: A moonlighting phage protein

profvrr in agarHosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson

A eukaryote without a mitochondrion, and using a phage enzyme to eliminate intracellular bacteria are two topics discussed by the TWiMers on this episode.

Right click to download TWiM#128 (38 MB .mp3, 78 minutes)

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world’s best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv.

TWiM 127: Subway Snowblowers and Men in Black

snowblowerHosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson

The TWiM team explores microbes in snowblower vents on the ocean floor, and cleavage of antibody molecules by a Mycoplasma protease.

Right click to download TWiM#127 (40 MB .mp3, 55 minutes)

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv.

TWiM 126: I’m not afraid of zebrafish and mice and bears (oh my!)

zebrafishHosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.

Right click to download TWiM#126 (49 MB .mp3, 67 minutes)

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv.

TWiM 125: A minimal cell operating system

Syn1.0Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

A deep sequencing study of commercially available probiotics, and design and synthesis of a minimal bacterial genome are the topics tackled by Vincent, Michael, and Michele on this episode of TWiM.

Right click to download TWiM#125 (42 MB .mp3, 58 minutes)

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv.

TWiM 124: Fungal pirates

Blastomyces dermatitidisHosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Vincent, Michael, and Michele reveal how a fungal protease blunts the innate immune response and promotes pathogenicity.

Right click to download TWiM#124 (44 MB .mp3, 63 minutes)

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv.

TWiM 123: A microbial MAGE

Microbial tradingHosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt

Guest: Harris Wang

Harris joins Vincent, Elio, and Michael to describe multiplex automated genome engineering, a method for targeting many modifications in a population of bacterial cells.

Right click to download TWiM#123 (52 MB .mp3, 76 minutes)

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by Microbe Magazine Podcast and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv.

TWiM 122: Mayonii, microRNAs, and the microbiome

Borrelia burgdorferiHosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Vincent, Michele, and Michael reveal the discovery of a new species of the spirochaete that causes Lyme disease, and fecal microRNAs that shape the gut microbiome.

Right click to download TWiM#122 (46 MB .mp3, 64 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by Microbe Magazine Podcast and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv.

TWiM 121: A plague of pathogens

Host: Vincent Racaniello

Guests: Rebekah Kading and Wyndham Lathem

From the ASM Biodefense and Emerging Diseases Research meeting, Vincent speaks with Rebekah and Wyndham about their work on Rift Valley Fever virus and other vector-borne pathogens, and the evolution and pathogenesis of Yersinia pestis, the agent of plague.

Right click to download TWiM#121 (42 MB .mp3, 58 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Grant Writing Webinar and 32nd Clinical Virology Symposium

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv.

TWiM 120: Snakes in trouble

snake fungal diseaseHosts: Vincent Racaniello and Elio Schaechter

Vincent and Elio marvel in the finding that a phage tail-like structure from a marine bacterium stimulates tubeworm metamorphosis, and reveal Ophidiomyces as a cause of snake fungal disease.

Right click to download TWiM#120 (35 MB .mp3, 49 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Grant Writing Webinar and 32nd Clinical Virology Symposium

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv.

About the Hosts of TWiM

Vincent Racaniello, Ph.D. (@profvrr) is Higgins Professor of Microbiology & Immunology at Columbia University Medical Center. He has been studying viruses for over 40 years. He teaches virology to undergraduate and graduate students, as well as medical, dental, and nursing students. His lectures are available online at iTunes University, YouTube, and Coursera.


Michael Schmidt, Ph.D. (TWiM) is the Professor and Vice Chairman of Microbiology and Immunology and Director of the Office of Special Programs at the Medical College of South Carolina. Dr. Schmidt is leading a team of infectious disease specialists from three health sciences centers and engineers from industry.

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