Nels and Vincent discuss new findings using phylogenetic approaches about how complex eukaryotic cells emerged from prokaryotic ancestors, which firmly place eukaryotes as a clade nested within the Asgard archaea.
Nels and Vincent provide insights into the mystery of mouse mummies on the summits of >6000 m Andean volcanoes, including whether they were living there and if so why?
Nels and Vincent discuss the observation that cells on a boundary of a solid tumor have higher growth rates compared to those in the center and how to model this difference using genome sequencing data.
Nels and Vincent review a study of the dogs of Chernobyl which reveals that genetically distinct populations with different amounts of western breed contributions to their genomes, the first step in assessing the effects of exposure to long-term ionizing radiation.
Nathan joins Nels and Vincent to discuss his approach to understanding how species adopt novel traits to overcome challenges, and its application to identifying coding and noncoding sequence changes that underlie mammalian hairlessness. Hosts: Nels…
Nels and Vincent discuss how evolution of changes in stop codon assignment might occur, and a novel mechanism for altering the meaning of translation stop codons discovered in a trypanosomatid with the apropos name, Blastocrithidia nonstop.
Nels and Vincent discuss the use of genome sequence data for over 4,000 domestic, semi-feral, and wild canids to understand the genetic drivers of canine behavior.
Florian Maderspacher from Current Biology joins Nels and Vincent to discuss a special issue of the journal on birds.
Nels and Vincent consider evidence that a single amino acid change in the TKTL1 gene might have led to greater neurogenesis in the frontal cortex of modern humans compared with Neanderthals.
Louise Moncla joins Nels and Vincent to review her use of genomics to understand emergence, evolution, and transmission of respiratory viruses including influenza virus H5N1, mumps virus, and SARS-CoV-2.