Matters Microbial #64: Making Sense of the Microbiome

November 7, 2024

Today, Dr. Patrick Schloss, Professor in the Department of Microbiology and Immunology in the School of Medicine at the University of Michigan, joins the #QualityQuorum to discuss how the human microbiome is studied, possible pitfalls in such data analysis, and what tools he and his coworkers have developed to lead toward repeatable, hypothesis-driven science.

Host: Mark O. Martin

Guest: Patrick Schloss

Download MM#64 (37 MB mp3, 61 min)
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  • An overview of how the gut microbiome is analyzed.
  • One of the articles discussed by Dr. Schloss exploring reproducibility in microbiome studies: “Identifying and Overcoming Threats to Reproducibility, Replicability, Robustness, and Generalizability in Microbiome Research.”
  • Another article discussed by Dr. Schloss, regarding the link between the microbiome and obesity:  “Looking for a Signal in the Noise:  Revisiting Obesity and the Microbiome.”
  • An article from Dr. Schloss’ research team that explores a link between the human microbiome and a type of colorectal cancer.
  • A link to the MOTHUR project, used to analyze microbiome data.
  • A link to a video by Dr. Schloss:  “Understanding Disease Through the Lens of the Microbiome.”
  • Dr. Schloss’ YouTube channel about data analysis.
  • Dr. Schloss’ research group website.
  • Dr. Schloss’ faculty website.

Intro music is by Reber Clark

Send your questions and comments to mattersmicrobial@gmail.com

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