In his weekly clinical update, Dr. Griffin discusses the recent increase in norovirus outbreaks, human cases of H5N1 avian influenza, before reviewing the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, how effective Molnupiravir is and provides information for Columbia University Irving Medical Center’s long COVID treatment center.
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Links for this episode
- Norovirus: Waste water scan for 11 pathogens (WastewaterSCan)
- Adolescent with Influenza A H5N1 infection (NEJM)
- Highly pathogenic avian Influenza A ( H5N1) virus infections in humans (NEJM)
- Emerging threat of H5N1 to human health (NEJM)
- US respiratory virus activity (CDC Respiratory Illnesses)
- In-hospital outcomes of healthcare-associated Coronavirus Disease 2019 (Omicron) versus healthcare-associated Influenza (CID)
- Waste water scan for 11 pathogens (WastewaterSCan)
- US respiratory virus activity (CDC Respiratory Illnesses)
- Weekly surveillance report: cliff notes (CDC FluView)
- RSV: Waste water scan for 11 pathogens (WastewaterSCan)
- RSV-Network (CDC Respiratory Syncytial virus Infection)
- US respiratory virus activity (CDC Respiratory Illnesses)
- Waste water scan for 11 pathogens (WastewaterSCan)
- COVID-19 deaths (CDC)
- COVID-19 national and regional trends (CDC)
- COVID-19 variant tracker (CDC)
- SARS-CoV-2 genomes galore (Nextstrain)
- Where to get pemgarda (Pemgarda)
- EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
- Fusion center near you….if in NY (Prime Fusions)
- CDC Quarantine guidelines (CDC)
- NIH COVID-19 treatment guidelines (NIH)
- Infectious Disease Society guidelines for treatment and management (ID Society)
- Drug interaction checker (University of Liverpool)
- Molnupiravir safety and efficacy (JMV)
- Real clinical effectiveness of Molnupiravir against 30-day mortality (OFID)
- Convalescent plasma recommendation for immunocompromised (ID Society)
- What to do when sick with a respiratory virus (CDC)
- When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
- Managing healthcare staffing shortages (CDC)
- Steroids, dexamethasone at the right time (OFID)
- Anticoagulation guidelines (hematology.org)
- Daniel Griffin’s evidence based medical practices for long COVID (OFID)
- Long COVID hotline (Columbia : Columbia University Irving Medical Center)Post-COVID Condition Risk Factors and Symptom Clusters and Associations with Return to Pre-COVID Health (CID)
- Letters read on TWiV 1180
- Dr. Griffin’s COVID treatment summary (pdf)
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv
The post TWiV 1180: Clinical update with Dr. Daniel Griffin first appeared on This Week in Virology.
I have heard about the discussion concerning whether or not a virus is alive. We know cells are alive, and they carry out the needs of the multicellular organism it is part of as well as it’s own molecular housekeeping. A virus does none of this. It does not live, it does not metabolize, create or destroy proteins, o9r do any of the things that are the hallmarks of life. It is a mechanism or program in stasis and as soon as it encounters the correct cellular attachment it delivers it’s program to the cell along with assorted ‘hacking’ molecules that make sure the cell runs the viruss’ program – which it does and in time the cell emits the newly created virus particles, via budding, lysis or ??
So since a virus does not metabolize on it’s own, when it is alone it is not alive. Even when in a cell, you might say the cell lives and has been diverted from it’s original task into a virus factory – so has become a living slave, as long as it lasts.