TWiV reveals a novel H5N1 reassortant virus in Cambodia, circulating vaccine derived poliovirus type 2 in more countries, circulation in the blood of humans of infectious parvovirus B19 coated with active proteases, and B cell receptor dependent enhancement of dengue virus infection.
Hosts: Vincent Racaniello, Dickson Despommier, Kathy Spindler, and Brianne Barker
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Download TWiV 1167 (62 MB .mp3, 103 min)
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Links for this episode
- MicrobeTV Discord Server
- MicrobeTV Fundraiser
- Novel H5N1 in Cambodia (medRxiv) 6:28
- More cVDVP2 circulation (polioeradication.org) 11:48
- Infectious parvovirus B19 with proteases (Nat Comm) 12:16
- B cell receptor enhancement of dengue disease (PLoS Path) 42:31
- Letters read on TWiV 1167 1:00:53
- Timestamps by Jolene. Thanks!
Weekly Picks 1:28:20
Brianne – See How Many Lives Vaccines Have Saved Around the World based on Lancet study
Dickson – 2024 Wildlife Photographer of the Year
Kathy – 450 Million year old arthropods preserved in fool’s gold. Primary article Pyrite video
Vincent – ‘We need to be ready for a new world’: scientists globally react to Trump election win
Listener Picks
Jack – Coronavirus vaccine update
Intro music is by Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
The post TWiV 1167: Virus cloak and entry first appeared on This Week in Virology.
I listen till the end!
Me too!
Hi Dr. Racaniello,
I was listening to TWIV 75 and noted the surprising comment
that influenza apparently does not evolve rapidly in domestic pigs. First, can
the domestic pig be an efficient influenza “mixing vessel” if it is
infrequently infected and produces little reassortment? Second, there is a
theory that the rapid movement of troops returning from WW1 in 1918 selected
for increased virulence of the Spanish Flu. (Virulent variants don’t need to
survive their hosts to propagate.) Wouldn’t the same concept apply to pigs, with
human handlers, high population densities, and agricultural fairs efficiently
transporting virus from pig to pig? I would expect selection for variants, or are my assumptions wrong?
Best,
Bruce
thank you for going over the red queen