TWiV notes the passing of virologist Diane Griffin, first H5N1 influenza virus in US pigs, Innate immune control of influenza virus interspecies adaptation via IFITM3, and antiviral trained innate immunity in alveolar macrophages after SARS-CoV-2 infection reduces secondary influenza A virus disease.
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker
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Download TWiV 1165 (63 MB .mp3, 105 min)
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Links for this episode
- MicrobeTV Discord Server
- MicrobeTV Fundraiser 6:07
- Diane Griffin passes (Johns Hopkins) 7:29
- Diane Griffin on TWiV 453 7:34
- First H5N1 influenza virus in US pigs (CIDRAP) 11:16
- IFITM3 controls interspecies influenza virus infection (Nat Comm) 15:58
- Trained innate immunity by alveolar macrophages (Immunity) 36:46
- Timestamps by Jolene. Thanks!
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Kathy – AAAS 150th anniversary video, celebrating scientists and Pew’s 2024 annual Trust in Science survey findings
Rich – Cats Basically Are a Liquid After All, Study Confirms
Alan – HHMI’s Beautiful Biology site
Vincent – EcoHealth Alliance Fights Back
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Intro music is by Ronald Jenkees
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Content in this podcast should not be construed as medical advice.
The post TWiV 1165: What doesn’t kill us primes our macrophages first appeared on This Week in Virology.
Wow! This episode is bookmarked for relistening. I was really drawn into
the scope and frank discussion of core concepts that literally run the
world of science as I have come to know it. I have always admired
Vincent and companies opinion regarding the need for openness and
transparency of science, but
even then I had no idea how incredibly dire the need was until it was
ranked it terms that your average joe could digest. I assumed that the
21st century system for funding, disseminating, and application of
scientific research is primarily based on universally grounded
principles itself and it appears that it is just not so. Competition is
an essential tool for some areas of science, how much did we gain as an
aside because Edison and Teslas ideas fought for supremacy? Never the
less it can also cost us unmeasured leaps in human progress when we
waste effort competing for the same end. Brilliant astronauts and
cosmonauts died fruitlessly because governments define the benefits of
competition as gospel rather then dynamic. Discouraging
cooperation/collaboration of data amongst scientific experts is
irrational far beyond sharing the vapid benefits of prestige and wealth a
hundred times over. In words that make the most sense to a tax payer
like me: why the hell isn’t the science of science based on the science
of science? There is no shades of grey here… A scientist should
believe that data and research is either open source or close minded,
period.
Definitely one of the most eyeopening episodes yet! I’ll share expecting that nothing has changed yet…