TWiV notes the passing of virologist Diane Griffin, first H5N1 influenza virus in US pigs, Innate immune control of influenza virus interspecies adaptation via IFITM3, and antiviral trained innate immunity in alveolar macrophages after SARS-CoV-2 infection reduces secondary influenza A virus disease.
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker
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Download TWiV 1165 (63 MB .mp3, 105 min)
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Links for this episode
- MicrobeTV Discord Server
- MicrobeTV Fundraiser 6:07
- Diane Griffin passes (Johns Hopkins) 7:29
- Diane Griffin on TWiV 453 7:34
- First H5N1 influenza virus in US pigs (CIDRAP) 11:16
- IFITM3 controls interspecies influenza virus infection (Nat Comm) 15:58
- Trained innate immunity by alveolar macrophages (Immunity) 36:46
- Timestamps by Jolene. Thanks!
Weekly Picks 1:21:01
Angela – See a giant ‘ghost particle’ detector and more — October’s best science images
Brianne – October 27 APoD: Bat nebula
Dickson – Nikon Small World Contest 2024 winners
Kathy – AAAS 150th anniversary video, celebrating scientists and Pew’s 2024 annual Trust in Science survey findings
Rich – Cats Basically Are a Liquid After All, Study Confirms
Alan – HHMI’s Beautiful Biology site
Vincent – EcoHealth Alliance Fights Back
Listener Picks
Hunter – Don’t stop me now: Queen’s Brian May on saving badgers — and the scientific method
Anne – Reasons to be cheerful
Intro music is by Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
The post TWiV 1165: What doesn’t kill us primes our macrophages first appeared on This Week in Virology.
Thought this comic was an interesting companion to Rich’s pick.
http://xkcd.com/1040/large/
Awesome.
Hi guys,
I LOVED this episode–very easy for the non-virologist to follow, for starters, and fascinating topic too.
Tyler mentioned that one of the Dengues he was discussing (#4?) was of a different clade. I know almost nothing about clades, so I don’t understand how two viruses that share a name can be in different clades? Is it similar to the situation with HepB and HepC where the names are similar, but the viruses are very different?
Thanks as always for a wonderful podcast
In taxonomy a clade is a group consisting of a species and its descendants. Viral clades refer to distinct subgroups of a particular virus, as determined by comparisons of genome sequences. For example, there are four groups of HIV-1, and in group M, there are least nine subtypes or clades. Dengue clades are all dengue virus, but different sequence groups.
Ah, thank you. That makes perfect sense.