From the Viruses of Microbes meeting in Cairns, Australia, TWiV speaks with Krystyna and Rob about their research on using bacteriophages to treat bacterial infections.
Hosts: Vincent Racaniello and Jolene Ramsey
Guests: Krystyna Dabrowska and Rob Lavigne
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Download TWiV 1153 (79 MB .mp3, 55 min)
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Links for this episode
Immune responses to phages (Front Immunol) 7:18
Engineering bacteriolytic enzymes (Front Immunol) 37:51
100 cases of phage therapy (Nat Micro) 27:56
Synthetic biology potential of bacteriophages (Nat Micro) 48:23
Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
The post TWiV 1153: Viruses that (can) make you well first appeared on This Week in Virology.
Thanks for the great (as always) episode this week. I feel like one important point was omitted during the discussion of the rational of vaccinating men against HPV. In addition to serving as a vector for cervical cancer in women, men are susceptible to anal cancer linked to HPV. Rates of anal cancer are particularly high in at-risk populations like men who have sex with men (JAMA. 1982;247(14):1988.) I don’t know if the cost-benefit analysis has been performed for vaccinating to prevent anal cancer, as it was with cervical cancer. But it is an important point that parents and individual patients should consider when thinking about getting vaccinated against HPV.
Great show though. The HPV vaccine is such an important accomplishment in modern medicine, and I appreciate you highlighting it.
Thanks,
Tom Hays
MD/PhD student, Mount Sinai School of Medicine.
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