Vincent, Dick, and Alan talk about insect and human dengue virus host proteins, equine vaccine for WNV and EEEV, return of swine flu to humans, spread of polio in Africa, and listener email.

Vincent, Dick, Alan, and Eric F. Donaldson discuss a new test for influenza H5N1, poliovirus in Minnesota, Koala retrovirus, batteries made from viruses, and SARS.

Vincent, Dick, Alan, and Saul Silverstein revisit an ebolavirus needlestick accident, and discuss the role of TLR3 in formation of Negri bodies, a New England college closed by norovirus gastroenteritis, hand, foot, and mouth disease outbreak in China, and the exit of herpes simplex virus from latency by synthesis of VP16.

Vincent, Alan, and Rich Condit converse about induction of polyomavirus replication in multiple sclerosis patients treated with the MS drug Tysabri, the extent of human polyomavirus infection, selection of influenza vaccines for the 2009-10 season, cowpox virus transmission from animals to humans, vaccinia-like virus infecting humans and cattle in Brasil, and poxviruses.

Vincent and Alan discuss cap-snatching by the hantavirus N protein and the influenza virus endonuclease, HIV-1 and Ebola virus antagonism of tetherin, and influenza pneumonia.

Vincent, Dick, and Alan discuss adenovirus type 36 and obesity, new influenza antiviral drugs, viral hemorrhagic septicemia virus of fish, and Ebola virus in pigs and pig farmers in the Phillipines.