TWiV explains the use of a neuronal cell line to study herpes simplex virus latency and reactivation, and a strategy for creating vaccines that induce antibodies against specific epitopes.
In the first episode for 2019, the TWiV team reviews the amazing virology stories of the past year.
The TWiV team notes the passing of Tom Steitz, an outbreak of acute flaccid myelitis in the US, a continuing Ebola virus outbreak in DRC, respiratory vaccinia due to inhalation of ground up rabbit skin, and how a human papillomavirus capsid protein directs virus-containing endosomes towards the nucleus.
From the 13th International Symposium on dsRNA viruses in Belgium, Vincent speaks with Harry Greenberg about his career and his work on rotaviruses, noroviruses, hepatitis B virus, and influenza virus.
The TWiVerinos discuss Nipah virus and the recent outbreak in India, and the first cast of polio in Papua New Guinea in 18 years.
The entire TWiV team visits The University of Texas in Austin to record episode #500 with guests Jinny Suh, Jason McLellan, and Jon Huibregtse.
Vincent and Rich recorded this episode at Vaccines in the 21st Century, a meeting held at the University of California, Irvine, where they spoke with Stacy Schultz-Cherry, Douglas Diekema, and Andrew Noymer about vaccine facts and fiction.
Vincent, Kathy, and Alan review the ongoing outbreak of Ebola virus in the Democratic Republic of the Congo, and the finding that mutations identified in the 2015 West African outbreak do not alter pathogenesis in animals.
Scott Hensley joins the TWiVites to review the current influenza season and presence of the virus in exhaled breath of symptomatic cases.
The TWiV team reviews the first FDA approved gene therapy, accidental exposure to poliovirus type 2 in a manufacturing plant, and production of a candidate poliovirus vaccine in plants.