Vincent, Alan, Matt and Kathy review isolation of a new coronavirus from two patients in the Middle East, and expansion of the enteric virome during simian AIDS.

Vincent, Alan, Rich, and special guest Dr. Kirsten Sanford talk about her career in science media, then consider whether smallpox eradication led to the AIDS pandemic, high fidelity RNA synthesis, and a new Ebola virus vaccine.

Vincent, Dick, and Alan talk about insect and human dengue virus host proteins, equine vaccine for WNV and EEEV, return of swine flu to humans, spread of polio in Africa, and listener email.

Vincent, Dick, Alan, and Eric F. Donaldson discuss a new test for influenza H5N1, poliovirus in Minnesota, Koala retrovirus, batteries made from viruses, and SARS.