Hosts: Vincent Racaniello, Dickson DespommierAlan DoveRich Condit, and Marc Pelletier

This Week in Virology and Futures in Biotech join together in a science mashup to talk about a virophage at the origin of DNA transposons, and unintended spread of a recombinant retrovirus.



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Marc – JotNot
Dickson – New bunyavirus in China (NEJM)
Rich – Listening to the Deep Ocean Environment (LIDO) recording of the Hatsushima earthquake (ScienceDaily article) – thanks Bridget!
Alan –Walter and Ina: A Story of Love, War, and Science
Vincent – Icosahedral light fixture (thanks, Eric!)

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icosahedron light

Rabbits Myxomatosis Trial WardangIsland 1938Hosts: Vincent Racaniello, Dickson DespommierAlan DoveRich Condit, and Grant McFadden

Vincent, Dickson, Alan, Rich, and Grant discuss a tanapoxvirus protein that inhibits tumor necrosis factor, purging tumors with myxoma virus, and destruction of the last known stocks of smallpox virus.

Click the arrow above to play, or rightight click to download TWiV #124 (74 MB .mp3, 103 minutes).

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Grant – A Short History of Nearly Everything by Bill Bryson
Dickson – An Inquiry into the Causes and Effects of the Variolae Vaccinae by Edward Jenner
Rich –
Selinah (Topsy Foundation) thanks Meghan!
Alan – Draft report (pdf) on WHO’s H1N1 response and NY Times summary
Vincent – 10 stunning science visualizations

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42Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich talk about XMRV integration sites in prostate tumor DNA, the decline effect and scientific method, and the first virus of Caenorhabditis nematodes.

Click the arrow above to play, or rightight click to download TWiV #123 (67 MB .mp3, 93 minutes).

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Rich – Einstein: His Life and Universe by Walter Isaacson (Aspen Institute)
Alan – Hi-definition microscopy movies in 3D
Vincent – Stan Maloy interview with Beatrice Hahn on the origins of HIV and malaria

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japanese macaquesHosts: Vincent Racaniello, Dickson Despommier, Alan DoveRich Condit, and Welkin Johnson

The complete TWiV crew teams up with Welkin Johnson to explore the other AIDS epidemic, infection of monkeys with simian immunodeficiency virus, and its restriction by the cellular protein TRIM5.

Click the arrow above to play, or right click to download TWiV #122 (77 MB .mp3, 147 minutes).

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Welkin – Supramap
Dickson – Science issue on visualizing data
Rich – Doonesbury weighs in on vaccines and autism

Alan – US National Vaccine Plan
Vincent – US Supreme Court decision on vaccine litigation (NY Times)

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Hosts: Vincent Racaniello, Michael Katze, Michael Gale, Deborah Fuller, and Shawn Iadonato

A conversation about careers in virology, systems biology, innate immunity, and antiviral research recorded at the University of Washington in Seattle.



Click the arrow above to play, or right click to download TWiV #121 (65 MB .mp3, 90 minutes).

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Michael K – Pasteur Museum
Deborah – Undaunted Courage by Stephen Ambros
Michael G – The Eighth Day of Creation by Horace Freeland Judson
Vincent –
The Emperor of All Maladies by Siddhartha Mukherjee

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viral huskies

BARDA_LOGOHosts: Vincent RacanielloRich Condit, and Ed Niles

Vincent, Rich, and Ed discuss the transition from academic scientist to government work, the general program of drug and vaccine development in the biodefense world and at BARDA, and career opportunities for scientists in government.

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Rich – Dark Sun: The Making of the Hydrogen Bomb by Richard Rhodes
Ed – Tenth anniversary of the human genome at Science Magazine
Vincent – Poliovirus fights back

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science journalismHosts: Vincent Racaniello and David Tuller

Vincent and journalist David Tuller converse about the state of science reporting by the press.

Click the arrow above to play, or right click to download TWiV #119 (43 MB .mp3, 60 minutes).

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Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich answer listener questions about vaccinia virus, fungal viruses, synthetic viruses, influenza vaccine, HeLa cells, multiplicity of infection, and much more.

Click the arrow above to play, or right click to download TWiV #118 (68 MB .mp3, 94  minutes).

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Alan – What you need to know about infectious disease
Rich – Bad Project (YouTube)
Vincent – Federal research center will help develop medicines

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panic virusHosts: Vincent RacanielloRich Condit, and Seth Mnookin

Vincent and Rich converse with Seth Mnookin, author of The Panic Virus, about vaccines, autism, thimerosal, and a contagion of human unreason run wild.

Click the arrow above to play, or right click to download TWiV #117 (69 MB .mp3, 96  minutes).

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Rich and Vincent – The Panic Virus by Seth Mnookin

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<p”>hive and feeding bottlesHosts: Vincent RacanielloAlan Dove, and Rich Condit

Vincent, Dickson, Alan, and Rich review an adenovirus-based vaccine strategy against drug addiction, a field trial of RNAi to prevent Israeli acute paralysis virus infection in honeybees, and suppression of avian influenza transmission in transgenic chickens.

Click the arrow above to play, or right click to download TWiV #116 (64 MB .mp3, 89 minutes).

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Dickson – Brian Deer’s investigation of Andrew Wakefield
Rich –
Photographic periodic table of the elements
Alan – Year of the bat (site one and site two)
Vincent – EteRNA (NY Times article)

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